Antibiotics

Question 1

Difference between Gram + and Gram -

Answer 1

Gram + has a thick cell well (purple stain)

Gram - has a thin cell wall and cannot be suppressed by penicillin (pink stain)

Question 2

S&S of infection

Answer 2

Fever
Chills
Sweats
Fatigue
Redness
Swelling
Elevated WBC
Pus

Question 3

Peak level definition

Answer 3

The highest amount of Rx present in blood plasma–most commonly 30 mins after IV administration and 30-90 mins after IM administration

Question 4

Trough level definition

Answer 4

Lowest level of drug present in the blood plasma

Question 5

When should a culture be taken from a patient?

Answer 5

Before administration of broad spectrum antibiotic

Question 6

Difference between bactericidal and bacteriostatic

Answer 6

Bactericidal kills the bacteria

Bacteriostatic inhibits growth of bacteria

Question 7

Therapeutic v. sub-therapeutic response

Answer 7

Therapeutic=symptoms improve

Sub-therapeutic=symptoms DO NOT improve

Question 8

If a patient is allergic to penicillin, what else are they likely allergic to?

Answer 8

Cephalosporins

Question 9

Carbapenums adverse effect

Answer 9

Seizures

Question 10

Tetracyclines adverse effect

Answer 10

Teeth discolorations (b/c is binds to Ca)

Question 11

Do not give _____ or _____ with tetracyclines.

Answer 11

Milk or antacids

Question 12

Tetracyclines are used to treat_____.

Answer 12

H. Pylori

Question 13

Aminoglycosides have a high chance of causing ____ and _____.

Answer 13

Nephrotoxiticy and ototoxicity

Question 14

Fluroquinolones adverse effect

Answer 14

Aquilles tendon rupture

Question 15

Rapid infusion of Vanco can cause______.

Answer 15

Red-man syndrome

Question 16

Peak and trough levels for Vanco

Answer 16

Peak level 18 to 50 mcg/ml

Trough level 10 to 20