Quiz 4 Flashcards
NSAIDs Patient Education
Discontinue ASA 1 week prior to surgery; take NSAID with food; DO NOT crush enteric tablets; watch for excessive bleeding
NSAID Interactions
Alcohol, anticoagulants, corticosteroids, concurrent use of other NSAIDs
ASA Toxicity (NSAID) Signs and Symptoms
Tinnitus, hearing loss, hyperventilation, dizziness, drowsiness
*No antidote
NSAIDs Adverse Effects
Gastric ulcers, GI bleeding, renal failure, MI, CVA
NSAIDs Contraindications
Allergy, Peptic Ulcer Disease, bleeding disorders, renal or hepatic disease, children with chicken pox or influenza (ASA), Cardiovascular Disease
NSAIDs Indications
Mild to moderate pain; fever; inflammation; dysmenorrhea (menstual cramps); inhibits platelet aggregation
NSAIDs MOA & Drug Effects
MOA: blocks the chemical activity of the enzyme COX
Drug effects: analgesic, antiinflammatory, antipyretic (fever), antiplatlet
Acetaminophen Patient Education
Acetaminophen is found in many combination medications (Vicodin, Norco)
Acetaminophen Toxicity & Antidote
Causes hepatic necrosis (>150mg/kg)
Antidote=Mucomyst
Acetaminophen Contraindications
Allergy, severe liver disease, G6PD Disease, alcohol (use with caution)
Acetaminophen Indications
Fever, mild to moderate pain, alternative for those who cannot use ASA
Acetaminophen MOA & Drug Effect
MOA: selective inhibition of Cyclooxygenase (COX) in the CNS
Drug effects: analgesic (pain reliever); antipyretic (fever reducer)
Opioid Nursing Implications
Assess: pain (0-10); respiratory depression, constipation, and watch for orthostatic hypotension
Opioid Interactions
Coadministration with: alcohol, barbiturates, benzodiazepines, CNS depressants
Opioid Toxicity Antidote
Narcan
Opioid Contraindications
Allergy, Biliary Tract surgery, severe asthma, head injuries, morbid obesity (sleep apnea), paralytic ileus
Opioid Adverse Effects
Sedation, pupils constric, respiratory depression, orthostatic hypotension, constipation, urinary retention
Opioid Indications
Pain, cough suppressant, diarrhea
Opioids are regulated by:
Controlled Substance Act (1970)
Opioid MOA &Drug Effect
MOA: Mu receptor agonists, similar to the body’s own endorphines
Drug effect: Opioid binds to mu receptor, relieving pain
Two classes of Opioid Analgesics
- ) Mild (Tylenol #3, Vicodin, Norco)
2. ) Strong (Morphine, Dilaudid, Fentanyl)
Reye’s Syndrome Definition & Causes
Causes swelling in the brain &liver
Suspected cause: use of ASA to treat a viral infection in children and teens (influenza or chicken pox)
Pain Tolerance (Psychological)
The amount of pain a person can endure without it interfering with normal function
Pain Threshold (Physiological)
The level of stimulus needed to produce the perception of pain