Quiz 5 Flashcards
What are the 3 structural defenses of the nervous system?
protection of the skull and spinal column, cushion of the CSF, restricted permeability of the blood brain barrier
What are the 2 cellular defenses of the nervous system?
phagocytes called microglial cells and macrophages
What are the normal biota of the nervous system?
there are none
Causative agent of meningitis
Neisseria meningitides
Causative agent of polio
Poliovirus
Causative agent of CJD
prions
Causative agent of rabies
Rabies Virus
Causative agent of Tetanus
Clostridium tetani
Causative agent of botulism
Clostridium botulinum
Tetanus and botulism are both
endospore forming anaerobes
C. tetani produces a powerful neurotoxin called
tetanospasmin
Symptoms of tetanus
clenching of the jaw, extreme arching of the back, flexion of the arms and extension of the legs
C. botulinum releases a neurotoxin called botulinum that results
in paralysis and loss of ability to contract muscles
Characteristics of Neisseria meningitides
gram negative diplococci
2 virulence factors of Neisseria meningitides
IgA protease that breaks down antibodies and a capsule to protect it from phagocytosis
How does N. meningitides damage blood vessels and what is it called?
Petechiae, it releases an endotoxin that stimulates certain WBC’s that release cytokines that damage the blood vessels
causative agent of malaria
Plasmodium genus
causative agent of AIDS
HIV virus
causative agent of endocarditis
Staphylococcus aureus
causative agent of plague
Yersinia pestis
causative agent of lyme disease
Borrelia burgdorferi
causative agent of anthrax
Bacillus anthracis
causative agent of infectious mononucleosis
Epstein Barr Virus