quiz 3 disease pathogenesis and treatment Flashcards

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1
Q

tetanus pathogenesis

A
  • tetanus toxin
  • A and B unit, B binds and A is toxic
  • neurons, effects GABA and glycine
  • spastic paralysis
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2
Q

tetanus treatment

A
  • human anti-tetanus immunoglobulin (dirty wounds)
  • penicillin
  • wound debridement
  • respiratory support
  • immunization with tetanus toxoid (1 dose if immunized more than 5 years go, or complete course if never immunized)
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3
Q

botulism pathogenesis

A
  • botulism toxin
  • A and B subunits, A is a protease
  • A, B, E serotypes most common
  • acetylcholine (flaccid paralysis)
  • toxin is heat labile (100C for 10 mins)
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