quiz 3 disease pathogenesis and treatment Flashcards
1
Q
tetanus pathogenesis
A
- tetanus toxin
- A and B unit, B binds and A is toxic
- neurons, effects GABA and glycine
- spastic paralysis
2
Q
tetanus treatment
A
- human anti-tetanus immunoglobulin (dirty wounds)
- penicillin
- wound debridement
- respiratory support
- immunization with tetanus toxoid (1 dose if immunized more than 5 years go, or complete course if never immunized)
3
Q
botulism pathogenesis
A
- botulism toxin
- A and B subunits, A is a protease
- A, B, E serotypes most common
- acetylcholine (flaccid paralysis)
- toxin is heat labile (100C for 10 mins)