mycobacterium Flashcards
1
Q
what are the two important clinical species of mycobacteria?
A
tuberculosis and leprae
2
Q
why are mycobacteria acid-fast?
A
lipids in cell walls
3
Q
who is most at risk for TB in the US?
A
elderly, AIDS, urban poor
4
Q
shape of tuberculosis
A
rod
5
Q
metabolism of tuberculosis
A
obligate aerobe
6
Q
tuberculosis colonies
A
clumps, due to hydrobic lipid nature
7
Q
what is the difference between mycolic acid and mycoside?
A
mycolic acid is a fatty acid while mycoside is mycolic acid attached to a carbohydrate to form a glycolipid
8
Q
what is cord factor?
A
two mycolic acids attached to a disaccharide, only found in virulent tuberculosis
9
Q
what is sulfatide?
A
cord factor + sulfate, prevents phagosome from fusing with lysosome that contains bactericidal enzymes
