quiz 2 Flashcards
coxiella burnetti
has a wide geographical distribution, aerosol transmission and can disseminate through the blood via monocytes, including the liver where they reside in kuppfer cells
does the immune system typically clear burnetti?
yes. 98% of the time. this does not involve antibodies
what virulence does burnetti have
has enzymes that degrade ROS. inhibits maturation of phagosomes,
what does interferon do to burnetti immune response
interferon gamma enhances phagocytosis of burnetti
what diseases do enteroviruses cause
conjunctivitis, herpangina, hand-foot and mouth disease, lower motor neuron paralysis.
do enterovirueses cause gastroenteritis
yes, but it is very mild and almost presents as symtpomatic
examples of enteroviruses
caxsackie, polio, rhino, hepA
echinococcus human infection
swallowing eggs.
what is the larval form called
the larval form arises from eggs is called the oncosphere
what happens to oncospheres
they usually develop into cysts in the liver and lung.
what happens to e. granulosus
dogs eat offal and continue the lifecycle.
how do we kill the echinococcus cysts
ethanol injection
what do we use for therapy
albendazole and praziquantal for 3 months.
how do we detect EBV infection
paul-bunnell test, monospot test, presence of IgM VCA antibodies
what do we use to treat ESBL
carbepenems, gentamycin, fluoroquinolones
