Quiz 10 - 12th of june Flashcards
1
Q
Pyrimidine
A
2
Q
Purine
A
3
Q
Adenine
A
4
Q
Guanine
A
5
Q
Cytosine
A
6
Q
Uracil
A
7
Q
Thymine
A
8
Q
Orotic acid
A
9
Q
PRPP
A
10
Q
β-alanine
A
11
Q
How are nucleotides created?
A
- Majority is made in the novo synthesis
- Remaining are created by reusing nitrogen bases, through a so-called salvage synthesis
12
Q
What enzyme catalyzes this reaction?
A
Glutamine: PRPP aminotransferase
13
Q
Enzymes involved in the biosynthesis of AMP and GMP
A
- Adenylosuccinate synthase
- Adenylosuccinate lyase
- IMP dehydrogenase
- XMP-glutamine amidotransferase
14
Q
Adenylsuccinyl synthase is inhibited by..
A
- AMP
14
Q
Glutamine: PRPP amidotransferase is regulated allosterically by…
A
- IMP, AMP and GMP - negative allosteric inhibitors
- PRPP - positive allosteric inhibitor
19
Q
Which enzyme is used here?
A
CPS 2 (carbamoyl phosphate synthetase 2)
20
Q
Which enzyme catalyzes these reactions?
A
- Aspartate transcarbamoylase
21
Q
Which enzyme catalyzes this reaction?
A
Orotidylate decarboxylase
22
Q
Which enzymes catalyze this reaction?
A
- pyrimidine monophosphate kinase
- pyrimidine diphosphate kinase
