QUIZ 1 - MSN 6204 Flashcards
Synbiotics are a combination of prebiotic and probiotic agents. This
combination is supposed to:
enhance the survival of the probiotic bacteria through the upper GIT
improve implantation of the probiotic strain in the colon
have a stimulating effect on the growth and/or activities of both the exogenously provided probiotic strain(s) and the endogenous inhabitants of the bowel
Do all of the above
Do none of the above
Do all of the above Correct!
Which of the following probiotic products has clinical trial evidence of efficacy for the treatment of infantile colic?
Culturelle Kids Probiotic
Natural Factors Children’s Multi Probiotic
Bio-Kult Infantis
Klaire Labs Ther-Biotic Children’s Chewable
Bio-Kult Infantis Correct!
Based on the most recent research, probiotics can be used to treat:
Endometriosis
Post-partum obesity
Mastitis
All of the above
All of the above
The probiotic strain Lactobacillus reuteri DSM17938 is found in which commercially-available probiotic preparation in the USA?
Bioceuticals UltraBiotic 45
Natren Healthy Trinity
Gerber Soother Colic Drops
Standard Process ProSynbiotic
Gerber Soother Colic Drops Correct!
What differentiates prebiotics from colonic foods?
Only colonic foods are fermented to produce short-chain fatty acids
Prebiotics are only utilized by a limited number of beneficial bacteria in the human GIT
Prebiotics have to be naturally-occurring, whereas colonic foods do not
Nothing differentiates them – they are different terms for the same thing
Only prebiotics are fermented to produce short-chain fatty acids
Prebiotics are only utilized by a limited number of beneficial bacteria in the human GIT
A probiotic strain that has demonstrated efficacy in the prevention of atopic eczema is:
Lactobacillus rhamnosus VRI-003
Lactobacillus rhamnosus HN001
Bifidobacterium lactis HN01
Lactobacillus acidophilus LAVRI-A1
Lactobacillus rhamnosus HN001
Probiotic characteristics are strain dependent. This means:
Desirable characteristics cannot be extrapolated across the species level
Strains within the same species may have differing therapeutic qualities
One cannot generalize research results conducted on one probiotic strain to another one, even if it is within the same species
All of the above
All of the above
Which prebiotic has been shown to increase microbial β-glucosidase activity in the colon?
Larch arabinogalactans
Galactooligosaccharides
Fructooligosaccharides
Lactulose
Apple pectin
Fructooligosaccharides
A prebiotic must have all the following characteristics except one. The exception is:
ingestion of the substance alters the colonic microflora ecosystem towards a healthier composition
the substance must be neither catabolized nor absorbed in the stomach or small intestine
ingestion results in changes that improve the health of the host
the substance must be naturally occurring
the substance must be a selective substrate only utilized by a limited number of beneficial bacteria
the substance must be naturally occurring
All of the following are desirable probiotic characteristics except one; choose the exception:
Human origin
Documented clinical safety
Adherence to the intestinal mucosa
Ability to colonize the human gastrointestinal tract (albeit only temporarily)
Antagonism against lactobacilli and bifidobacteria
Antagonism against lactobacilli and bifidobacteria
What is the best rationale to base your prescribing of a particular probiotic supplement on?
Your clinical experience
Your colleagues’ clinical experience
Choose the supplement with the highest CFU (colony forming units)
Clinical trial level evidence of efficacy
Claims made in a manufacturers’ brochure
Clinical trial level evidence of efficacy
Which of the following is not a mechanism by which probiotics work:
Conversion of excess intestinal gases to water
Competition for space and nutrients with potential
pathogens
Production of selectively-acting anti-microbial substances Via interaction with immune cells along the GIT
Via production of beneficial compounds in the GIT (e.g., polyamines)
Conversion of excess intestinal gases to water
Which of the following is not a common side effect from prebiotic administration?
Flatulence
Abdominal distension
Sore joints
Abdominal bloating
Abdominal pain
Sore joints
What is the prebiotic of choice to prevent Traveler’s diarrhea?
Fructooligosaccharides
Galactooligosaccharides
Larch arabinogalactans
Raffinose
Galactooligosaccharides
What is the general rule of dosing with prebiotic compounds?
Start low and slowly work your way up to the ideal therapeutic dose
Start with the ideal therapeutic dose and if this causes symptoms, slowly reduce the dose until it appears well-tolerated
They work synergistically, so it is best to give a number of them
concurrently to maximize effectiveness
None of the above
Start low and slowly work your way up to the ideal therapeutic dose