quinolones Flashcards
1
Q
cautions
A
- Can prolong the QT interval; conditions that predispose to seizures; diabetes (may affect blood glucose); exposure to excessive sunlight and UV radiation should be avoided during treatment and for 48 hours after stopping treatment; G6PD deficiency; history of epilepsy; myasthenia gravis (risk of exacerbation); psychiatric disorders
- Quinolones cause arthropathy in the weight-bearing joints of immature animals and are therefore generally not recommended in children and growing adolescents. However, the significance of this effect in humans is uncertain and in some specific circumstances use of ciprofloxacin may be justified in children.
2
Q
Cautionary and advisory labels
A
Do not take milk, indigestion remedies, or medicines containing iron or zinc, 2 hours before or after you take this medicine
3
Q
INTERACTION
A
NSAIDs inc risks of convulsions
4
Q
INTERACTION 2
A
QT-PROLONGATION so inc ris with SSRIS, Amiodarone, quinine , macrolide and antipsychotics
5
Q
INTERACTIONS 3
A
Increased risk of convulsions with THEOPHYLLINE as quinolone is an enzyme inhibitor , so increases its concentration.