H.influenza prophylaxis Flashcards
Haemophilus influenzae type b (Hib) Infection: Prevention of Secondary Disease
Q: What is the main goal of antibacterial prophylaxis in Hib infection?
A: To reduce the risk of secondary disease by eliminating asymptomatic pharyngeal carriage of Hib.
Q: What is the recommended timing for giving antibacterial prophylaxis to confirmed or probable cases of invasive Hib disease in children under 10 years and those with vulnerable individuals in their household?
A: Prior to hospital discharge.
Q: Who should receive antibacterial prophylaxis among household contacts of a confirmed or probable index case?
A: All household contacts if there is a vulnerable individual in the household.
Q: In what circumstances is antibacterial prophylaxis recommended for all room contacts, including staff, in a pre-school or primary school setting?
A: During an outbreak (**2 **or more cases of invasive Hib disease within 120 days).
Q: When should antibacterial prophylaxis be offered to all eligible contacts in relation to the illness onset in the index case?
A: Up to 4 weeks after illness onset in the index case.
Q: What additional measure should be considered alongside antibacterial prophylaxis following a case of invasive Hib disease?
A: Vaccination with a Hib-containing vaccine.
Q: What are the f**irst-line **choices for antibacterial prophylaxis in Hib infection?
A: Rifampicin.
Q: What are the alternatives if rifampicin is unsuitable for antibacterial prophylaxis in Hib infection?
A: Ceftriaxone [unlicensed], oral ciprofloxacin [unlicensed], or azithromycin [unlicensed], though effectiveness in healthy individuals has not been determined.
A: To reduce the risk of secondary disease by eliminating asymptomatic pharyngeal carriage of Hib.
Q: What is the recommended timing for giving antibacterial prophylaxis to confirmed or probable cases of invasive Hib disease in children under 10 years and those with vulnerable individuals in their household?
A: Prior to hospital discharge.
Q: Who should receive antibacterial prophylaxis among household contacts of a confirmed or probable index case?
A: All household contacts if there is a vulnerable individual in the household.
Q: In what circumstances is antibacterial prophylaxis recommended for all room contacts, including staff, in a pre-school or primary school setting?
A: During an outbreak (2 or more cases of invasive Hib disease within 120 days).
Q: When should antibacterial prophylaxis be offered to all eligible contacts in relation to the illness onset in the index case?
A: Up to 4 weeks after illness onset in the index case.
Q: What additional measure should be considered alongside antibacterial prophylaxis following a case of invasive Hib disease?
A: Vaccination with a Hib-containing vaccine.
Q: What are the first-line choices for antibacterial prophylaxis in Hib infection?
A: Rifampicin.
Q: What are the alternatives if rifampicin is unsuitable for antibacterial prophylaxis in Hib infection?
A: Ceftriaxone [unlicensed], oral ciprofloxacin [unlicensed], or azithromycin [unlicensed], though effectiveness in healthy individuals has not been determined.
H-INFLUEZA-RRR
Prophylaxis drug is
RRRIFAMPICIN
Haemophilus influenzae type b (Hib) Infection: Prevention of Secondary Disease
Q: What is the main goal of antibacterial prophylaxis in Hib infection?
Q: What is the recommended timing for giving antibacterial prophylaxis to confirmed or probable cases of invasive Hib disease in children under 10 years and those with vulnerable individuals in their household?
A: Prior to hospital discharge.
Q: Who should receive antibacterial prophylaxis among household contacts of a confirmed or probable index case?
A: All household contacts if there is a vulnerable individual in the household.
Q: In what circumstances is antibacterial prophylaxis recommended for all room contacts, including staff, in a pre-school or primary school setting?
A: During an outbreak (2 or more cases of invasive Hib disease within 120 days).
Q: When should antibacterial prophylaxis be offered to all eligible contacts in relation to the illness onset in the index case?
A: Up to 4 weeks after illness onset in the index case.
Q: What additional measure should be considered alongside antibacterial prophylaxis following a case of invasive Hib disease?
A: Vaccination with a Hib-containing vaccine.
Q: What are the first-line choices for antibacterial prophylaxis in Hib infection?
A: Rifampicin.
Q: What are the alternatives if rifampicin is unsuitable for antibacterial prophylaxis in Hib infection?
A: Ceftriaxone [unlicensed], oral ciprofloxacin [unlicensed], or azithromycin [unlicensed], though effectiveness in healthy individuals has not been determined.
Haemophilus influenzae type b (Hib) Infection: Prevention of Secondary Disease
Q: What is the main goal of antibacterial prophylaxis in Hib infection?
A: To reduce the risk of secondary disease by eliminating asymptomatic pharyngeal carriage of Hib.
Q: What is the recommended timing for giving antibacterial prophylaxis to confirmed or probable cases of invasive Hib disease in children under 10 years and those with vulnerable individuals in their household?
A: Prior to hospital discharge.
Q: Who should receive antibacterial prophylaxis among household contacts of a confirmed or probable index case?
A: All household contacts if there is a vulnerable individual in the household.
Q: In what circumstances is antibacterial prophylaxis recommended for all room contacts, including staff, in a pre-school or primary school setting?
A: During an outbreak (2 or more cases of invasive Hib disease within 120 days).
Q: When should antibacterial prophylaxis be offered to all eligible contacts in relation to the illness onset in the index case?
A: Up to 4 weeks after illness onset in the index case.
Q: What additional measure should be considered alongside antibacterial prophylaxis following a case of invasive Hib disease?
A: Vaccination with a Hib-containing vaccine.
Q: What are the first-line choices for antibacterial prophylaxis in Hib infection?
A: Rifampicin.
Q: What are the alternatives if rifampicin is unsuitable for antibacterial prophylaxis in Hib infection?
A: Ceftriaxone [unlicensed], oral ciprofloxacin [unlicensed], or azithromycin [unlicensed], though effectiveness in healthy individuals has not been determined.
