Quick Drugs Flashcards by Sereen Feroz

Q

Metformin drug clas

A

Biguanide

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Q

Metformin MOA

A

↑Peripheral insulin sensitivity
Inhibits hepatic gluconeogenesis

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Q

Gliclazide drug class

A

Sulphonylurea

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Q

Gliclazide MOA

A

Depolarise islet cells in pancreas
∴ ↑ insulin release

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Q

Pioglitazone drug class

A

Thiazolindinediones

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Q

Pioglitazone MOA

A

↑ Peripheral insulin sensitivity

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Q

Dapaglifozin Drug CLass

A

SGLT-2 i

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Q

Dapaglifozin MOA

A

↑ Urinary glucose loss

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Q

Sitagliptin Drug class

A

DPP4-i

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Q

Sitagliptin MOA

A

Inhibit GLP1 breakdown

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Q

Exenatide Drug class

A

GLP1 Analogue

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Q

Exanetide MOA

A

↑ Insulin sensitivty and secretion

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Q

Acarbose Drug Class

A

Intestinal Alpha-Glucosidase inhibitor

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Q

Acarbose MOA

A

Delay intestinal carb absorption

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Q

S/E Biguanide

A

Lactic Acidosis

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Q

CI Metformin

A

eGFR < 30
ml/kg/hour ? Unit?

Q

S/E Sulphonlyurea

A

Hypoglycaemia
Weight gain

Q

S/E Thiazolidinedione

A

Fluid rentention
Weight grain
Worsening HF

Q

S/E SGLT2 -i

A

DKA if used with insulin
↑ UTI

Q

S/E DPP4-i

A

Hypoglycaemia
GI upset

Q

S/E GLP1 Analgoes

A

Hypoglycaemia
GI upset
↑Risk of pancreatitis

Q

S/E Intestinal Alpha=Glucosidase inhibitor

A

Flatulence
GI disturbance

Q

A