Patho of Big Diseases Flashcards

Big key points for marks in SAQ

1
Q

Goodpasture’s

A

Autoimmune destruction of Type 4 collagen in lungs and kidneys
Type 2 HS

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2
Q

Post-Strep

A

Type 3 HS
Immune complexes trapped in sub-epithelial - between BM and podocytes

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3
Q

IgA Nephropathy

A

Type 3 HS
Abnormal IgA deposited in mesangium

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4
Q

Asthma

A

Hypersensitivity of airways
Mast cell mediated
Bronchoconstriction

-> Inflamed bronchioles, mucus hypersecretion

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5
Q

COPD : Chronic Bronchitis

A

Hyperplasia and hypertrophy of mucus glands
+ Chronic inflammation in bronchial walls
∴ ↑ mucus, ↓ Lumen

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6
Q

COPD : Emphysema

A

Destruction of elastin layer
∴ distal air trapping
∴ bullae might be formed

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7
Q

Pneumonia

A

Lung parenchyma inflammation

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8
Q

Parkinson’s

A

Dopamine in the pars compacta of the substantia nigra

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9
Q
A
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