Patho of Big Diseases Flashcards
Big key points for marks in SAQ
1
Q
Goodpasture’s
A
Autoimmune destruction of Type 4 collagen in lungs and kidneys
Type 2 HS
2
Q
Post-Strep
A
Type 3 HS
Immune complexes trapped in sub-epithelial - between BM and podocytes
3
Q
IgA Nephropathy
A
Type 3 HS
Abnormal IgA deposited in mesangium
4
Q
Asthma
A
Hypersensitivity of airways
Mast cell mediated
Bronchoconstriction
-> Inflamed bronchioles, mucus hypersecretion
5
Q
COPD : Chronic Bronchitis
A
Hyperplasia and hypertrophy of mucus glands
+ Chronic inflammation in bronchial walls
∴ ↑ mucus, ↓ Lumen
6
Q
COPD : Emphysema
A
Destruction of elastin layer
∴ distal air trapping
∴ bullae might be formed
7
Q
Pneumonia
A
Lung parenchyma inflammation
8
Q
Parkinson’s
A
Dopamine in the pars compacta of the substantia nigra
9
Q
A