Questions wrong Flashcards
Monoallelic expression mechanism is due to what?
Altered chromatin structure and differential expression of an antisense RNA transcript
Differential expression of an antisense RNA transcript
Blocking of enhancer by insulator and altered chromatin in gene promoter
Feeding agouiti mice a diet rich in____ does what?
Methyl rich nutrients can lead to a change in epigenetic patterns
Where can RNA interference regulate gene expression
Post transcriptionally
True or false ADAR functions in RNA editing
True
What are inherited defects that are due to alterations in the DNA sequence called?
Mutations
An individual with kleinfelters syndrome has what
A single Barr body
How many amounts of sequence reads are under taken simultaneously on the illumina platform
Millions to billions
True or false A 2-mb location at 15q11-13 silences Angel man syndrome and Prader-Wili syndrome
False,it doesnt silence, it maps
Does a Cpg island refers to G followed by a C in the 5’ to 3’ direction?
Nope
Where does CRISPR naturally occur and what type of system is it?
Occurs in bacteria and is apart of the immune system
True or false, a major issue associated with CRISPR is off targeting
True
As PCR reactions proceed, at one point fluorescence increases. What process explains this
TAQ man probe molecules are degraded into nucleotides
Where are XIST transcript levels upregulated?
On the inactive X chromosome
True or false
Dicer is the component of the RNAI pathway that confers inheritance of siRNA induced silencing
False
What can CRISPR cas 9 do?
It can edit DNA in a wide range of organisms
