Questions - Misc 03 Flashcards
Does alcohol sterilize?
No it cannot kill spores, it disinfects only.
What is unique about bacterial cell walls that we don’t have?
Peptidoglycan
What two rings are present in penicillin?
Beta-lactam
Thiazolidine
What does the sidechain of penicillins determine?
The spectrum of activity
What two rings are present in cephalosporins?
Beta-lactam
Dihydrothiazine
2R groups
Which lactams are available for people with penicillin allergies?
Monobactams like Aztreonam
Which is a beta-lactamase inhibitor that is going to bind to the beta-lactamase enzyme and prevent it from attacking the beta-lactam ring of a beta-lactam antibiotic?
Clavulanic acid
Tazobactam
What does bacitracin inhibit?
Peptidoglycan synthesis
What does vancomycin prevent?
The formation of the interbridge of gram-positive cells
People who were put on this medication usually have a horrendous infection and are not responding to other bacteria because they are resistant. Their flora is usually depleted because of being on antibiotics for a long time (clostridium difficile related pseudomembranous colitis)
Daptomycin
What do quinolones act on?
DNA gyrases
What inhibits transcription by acting on the bacterial RNA polymerase enzyme?
Rifampin
Which antibiotic can turn body fluids orange in color?
Rifampin
Which of the five antibiotics that inhibit the 50 S subunit?
Chloramphenicol Clindamycin/Lincomycin Macrolides Ketolides Oxazolidinones
Which are the two antibiotics that inhibit the 30 S subunit?
Tetracyclines
Aminoglycosides
