Bacteriology - Background Flashcards

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1
Q

Are bacteria haploid or diploid?

A

Haploid with the genome in the cytoplasm

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2
Q

What are the bacterial arrangements?

A
  • Coccus
  • Rod/Bacillus
  • Vibrio
  • Spirillum
  • Spirochete
  • Branching Filaments
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3
Q

What profile will give you which antibiotics a particular bacteria is susceptible to?

A

Anti-biogram

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4
Q

Which are the two biochemical analysis methods to identify bacteria?

A
  • Sugar fermentation (lactose +/-)

- Enzyme production (coagulase+/-, Urease+/-)

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5
Q

Coagulase production is an important virulence factor for which bacteria?

A

Staph Aureus

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6
Q

What is the taxonomic structure?

A

Dumb Kings Play Chess On Funny Green Squares:

  • Domain
  • Kingdom
  • Phylum
  • Class
  • Order
  • Family
  • Genus (Escherichia)
  • Species (coli)
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7
Q

Which are the structural features of a bacterium?

A
  • Appendages
  • Cell envelope
  • Cytoplasmic
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8
Q

Which are the two major groups of appendages?

A
  • Flagella and axial filaments: provide motility

- Fimbriae and pili: provide attachment points or channels

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9
Q

What is the function of the flagella?

A

Chemotaxis: movement in response to chemical signals

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10
Q

Which type of bacteria has a periplasmic flagella (aka endoflagella or axial filament)?

A

Spirochetes (syphillis). It is used for a corkscrew type of motion. It is internal.

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11
Q

Which type of bacteria is a pili found in (gram + or -)?

A

Gram negative

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12
Q

How does the capsule provide a virulence factor for the bacteria?

A

It makes the bacteria slippery so it does not let your immune cells grab a hold of the bacteria

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13
Q

What is the capsule (aka Glycocalyx) made of and what is its function?

A

Made of polysaccharide polymers. Function is adherence and immune evasion.

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14
Q

What are the two forms of the outer polysaccharide layer?

A

if it is structured really well and close to the cell it is called a capsule, if it is kind of loose and a slime around the bacteria it is called a slime layer ( the old term is glycocalyx)

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15
Q

What are the 2 main components of the cell wall?

A
  • peptidoglycan

- membrane(s)

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16
Q

What are the functions of the cell wall?

A
  • Maintain cell shape

- Maintain osmotic balance

17
Q

What are the 2 main types of cell walls?

A
  • Gram +

- Gram -

18
Q

What are the characteristics of Gram + cell walls?

A
  • Thick peptidoglycan
  • Teichoic acid
  • also cytoplasmic (cell membrane and Lipoteichoic acid
19
Q

What are the characteristics of Gram - cell walls?

A
  • Thin peptidoglycan
  • LPS (lipopolysaccharide)
  • also cytoplasmic (inner) membrane, outer membrane, periplasmic space
20
Q

What cell wall type do penicillins target?

A

Gram +. They target peptidoglycan synthesis