Question 2 of 2 Flashcards
differences between mitosis and meiosis
Mitosis
- 2 identical daughter cells
- 46 chromosomes (diploid)
- Function; growth and repair
- Somatic daughter cells produced
Meiosis
- 4 different daughter cells
- 23 chromosomes (haploid)
- Function; production of gametes
- Gametes produces
Variation
• Difference between individuals of the same species
• Allows for survival in their environment
• Variation occurs through;
- Random assortment of chromosomes
- Crossing over
- Non-disjunction
- Random fertilisation
random assortment
® When cells divide by meiosis to form sex cells, chromosomes are copied
® Chromosomes are separated twice
® Direction that the chromosomes move is totally random
- Results in millions of different combinations
crossing over
® Occurs when a small section of chromosomes swaps with a small section of a homologous pair
- Results in sex cells carrying different alleles of a gene
Non-disjunction
® When a chromosomes pair do not separate properly during meioisis
- Down syndrome is caused by non-disjunction
Random fertilisation
® Male releases millions of sperm, each slightly different
® 50% of sperm carry ‘X’’ chromosome and 50% carry ‘Y’ chromosome
® Thus, gender selection is random
- Gender depends on which sperm fertilises the egg
Cancer
® Uncontrolled cell division occurring in mature organisms
® Causes abnormal tissue growths
® Neoplasm:
- Abnormal growth of tissue
- Three types; Benign, Malignant and Potentially malignant
Gene mutation
Proto-oncogenes - normally function to stimulate cell growth
• When mutated, become oncogenes which cause uncontrolled cell division
Tumour suppressor genes - normally function to slow cell division, inhibiting division of unhealthy cells
- When mutated, uncontrolled cell division can occur
Inherited genes - variants in genes which can increase the risk of cancer
- E.g breast cancer is associated with mutations in BRCA1/BRCA2 genes
factors that cause cancer
- Genetics -> proto-oncogenes etc
- Environment -> physical, chemical, biological
- Loss of immunity -> weakened immune system