Quantitative Genetics 2

Question 1

Fishers fundamental theorem

Answer 1

The rate at which the mean fitness of a population increases is proportional to the additive genetic variation

Question 2

Breeders equation

Answer 2

R (response to selection)=h2S
R is the difference in trait mean between generations
Hn (H2) is the narrow sense heritability va/vp
S is the difference and treat me in between all the parental generation and the selected parents

Question 3

The response Have a quantitative trade to directional selection also depends on three things

Answer 3

1. Mode of selection
2. Genomic architecture or the trait
3. Genetic correlations between traits

Question 4

Mode of selection

Answer 4

Directional: mean-change variance-no change
Stabilizing: mean-no change variance-decrease
Disruptive: mean-no change variance-increas

Question 5

Genomic architecture of the trait

Answer 5

How many polymorphic loci affect the trait, effects of the loci, dominance or interactions, plasticity (vgxve)

Question 6

Genetic correlations between traits

Answer 6

Can arise from pleiotropy or linkage disequilibrium

One gene of major effect

Question 7

Heritability and response to selection are higher for what kind of traits

Answer 7

The ones that have less effect on fitness

Question 8

How do other micro evolutionary forces affect quantitative traits

Answer 8

Effects should be a sum of their effects (like no random mating and mutation on Va)

Question 9

What does mutation do

Answer 9

Generated variation quickly for traits controlled by large number of loci