Pyruvate Oxidation + Kreb's Cycle

Question 1

Step 1 of pyruvate oxidation

Answer 1

• Carbon dioxide from the pyruvate is removed

Question 2

Step 2 of pyruvate oxidation

Answer 2

NAD+ is reduced and becomes NADH + H+

Question 3

Step 3 of pyruvate oxidation

Answer 3

• Acetyl is attached to Co-enzyme A

Question 4

What does CO-A stand for?

Answer 4

Co-enzyme A

Question 5

What is special about Step 5 of the Kreb’s Cycle

Answer 5

• Only place in the kerb’s cycle where ATP is created instantaneously
• Substrate level phosphorylation

Question 6

What is GTP

Answer 6

• Sister molecule to ATP but slightly less effective
• Full name: Guanosine Triphosphate

Question 7

Summary of Pyruvate Oxidation

Answer 7

• Begin with pyruvate (3 carbons) which undergoes changes to become acetyl (2 carbons)
  1. Decarboxylation (-CO2)
  2. Oxidation by NAD+
  3. Co-enzyme A attaches to acetyl

Question 8

Summary of the Krebs Cycle

Answer 8

• Oxaloacetate (4 carbons) attaches to acetyl (2 carbons) this triggers the beginning of the Kreb’s Cycle
• 2 cycles per glucose
• By the end of the cycle all carbons from glucose are oxidized and have been removed as CO2

Question 9

Location of the Kreb’s Cycle

Answer 9

Mitochondrial Matrix