Pyruvate Alternatives

Question 1

Lactic Acid Fermentation

Answer 1

Pyruvate is reduced to lactate when no O2 (Exercising, flight or flight, ect..)

Question 2

Pyruvate to lactate

Answer 2

Lactate dehydrogenase

Question 3

Alcohol Fermentation

Answer 3

Pyruvate to ethanol and CO2

Question 4

Pyruvate to ethanol and CO2

Answer 4

Only in yeast and some bacteria

Question 5

Pyruvate Kinase Deficiency(PKDef)

Answer 5

Autosomal recessive disease shortening lifespan of RBC’s by limiting last step of glycolysis. Leads to hemolytic anemia.
Common in: Beagle, Cairn Terrier, Pug, West Highland White Terrier

Question 6

Glycolysis Associated Anemia

Answer 6

RBCs depend on glycolysis for energy and when energy needs not met, they lyse. This creates hemolytic anemia.