Glycogensis Flashcards
1
Q
Step 1
A
Glucose is phosphorylated to glucose-6-phosphate
2
Q
Glucose to glucose 6-phosphate
A
Hexokinase (muscle) or glucokinase (liver)
3
Q
Step 2
A
Glucose-6-phosphate is isomerized to glucose-1-phosphate
4
Q
Glucose 6-phosphate to glucose 1-phosphate
A
Phosphoglucomutase
5
Q
Step 3
A
Uridine 5ʹ-diphosphate-glucose is formed
6
Q
Glucose 1-phosphate to UDP
A
UDP-glucose pyrophosphatase
7
Q
Step 4 (Elongation)
A
Glycogenin (GN) glucosylates a tyrosine residue
alpha 1-4 glucosyl unit (adding glucose)
8
Q
Step 5 (Branching)
A
α-1,6-glucosyltransferase (aka branching enzyme) transfers glucosyl units from the
outer end of a glycogen chain to an alpha-1,6 position on a neighboring chain
9
Q
UDP to alpha 1-4 glucosyl unit
A
Glycogen synthase
10
Q
1-4 glucosyl unit to glycogen
A
Branching enzyme
