Pyelonephritis Flashcards

1
Q

what is this?

A

infection in renal pelvis and parenchyma

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2
Q

risk factors?

A
  • female
  • structural urological abnormalities
  • diabetes
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3
Q

most common causative organisms?

A
  • E.Coli
  • Klebsiella
  • Pseudomonas
  • Enterococcus
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4
Q

Presentation?

A
  • loin to groin pain
  • dysuria
  • frequency
  • haematuria

systemically:

  • pyrexia
  • rigors
  • nausea & vomiting
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5
Q

O/E?

A

pain on bimanual palpation of kidney

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6
Q

ix?

A
  • urine dipstick
    • blood
    • protein
    • leucocytes - produced by neutrophils
    • nitrites
  • Urine MC&S
  • Bloods
    • FBC, CRP, LDH
    • cultures
  • USS useful to screen for underlying urological abnormalities
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7
Q

how are nitrites produced?

A

gram negative organisms metabolise nitrates in urine (normal) to nitrites

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8
Q

Mx?

A
  • Broad spectrum Abx until culture & sensitivities available
    • co-amoxiclav
  • then targeted empirical Abx
  • IV fluids
  • Analgesia
  • Antipyretics
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9
Q

complications of chronic pyelonephritis?

A
  • leads to scarring of renal parenchyma
  • can result in CKD
  • can result in abscess and/or pus in or around the kidney
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10
Q

what investigation is done in recurrent pyelo to assess for complications?

A

DMSA scan

involves injecting radiolabelled DMSA into kidneys and this will show any areas of scarring

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11
Q

treatment of it in the community?

A

Co-amox / ciprofloxacin for 7-10days

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