Putthoff - CIS #2 Flashcards
Subdural and Epidural bleeds typically occur over the _________ of the brain.
Convexities
Where do hypertensive bleeds typically occur?
Pons and Basal Ganglia (Deep parenchymal structures)
Which etiology is involved in a bleed into the Epidural Space?
Trauma
Which etiology is involved in a bleed into the Subdural Space?
Trauma
Which etiologies are involved in a bleed into the Subarachnoid Space?
- AVM
- Rupture of Saccular Aneurysms
- Trauma (Typically associated with underlying contusions)
Which etiologies are involved in a bleed into the Intraparenchymal space?
- Hemorrhagic conversion of an ischemic infarction
- Cerebral amyloid Angiopathy
- Hypertension (lacunar infarcts)
- Tumors
- Trauma (selective involvement in the areas where the brain is going to come in contact with the skull)
An isolated basilar subarachnoid hemorrhage is typical of a _________ .
Saccule Aneurysm Bleed (Berry)
Which disease is going to present with an accumulation of AB protein?
Alzheimers disease
- Alzheimers Disease
- FTLD
- Parkinson Disease
- Progressive Supranuclear Palsy
- Corticobasal Degeneration
All present with which protein?
Tau
Which two disease can present with the TPD-43 and FUS protein?
- ALS
2. FTLD
Parkinson Disease and Multiple System Atrophy can both present with which protein?
Alpha-synuclein
- Huntington Disease
- Some forms of spinocerebellar ataxia
- Spinal bulbar muscular atrophy
All present with which protein?
Polyglutamine aggregates (different proteins per disease)
What is the initiating event for Alzheimers Disease?
Starts with AB deposition
How can you differentiate Alzheimers Disease from FTLDs, PSP, and Corticobasal Degeneration?
They both have Tau protein BUT Alzheimers Disease is the only one with AB protein!
Primary CNS lymphoma (B-Cells) is almost exclusively found in _______ patients.
HIV
