Eye Pathology Flashcards

1
Q

What is the most common malignancy of the eyelid?

A

Basal Cell carcinoma

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2
Q

Basal Cell carcinoma in the eyelid is going to prefer which two places?

A
  1. Lower Eyelid

2. Medial canthus

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3
Q

True or False. Primary melanomas of the eyelid skin are extremely rare.

A

True

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4
Q

Diseases that increase orbital contents therefore displace the eye forward, a condition known as __________ .

A

Proptosis

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5
Q

Which neoplasm of the eyelid is going to have a tendency to metastasize and is therefore a serious and potentially life-threatening condition?

A

Subaceous carcinoma

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6
Q

Infection with __________ may produce significant conjunctival scarring.

A

Chlamydia trachomatis

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7
Q

Malignant neoplasms arising in the eyelid and conjunctiva tend to spread to ________ and ______ Lymph nodes.

A
  1. Parotid

2. Submandibular

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8
Q

_________ is the part of the conjunctiva that contains a lot of lymphatics.

A

Fornix

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9
Q

Pinguecula and pterygium appear as submucosal elevations on the conjunctiva. Which one is going to typically originate in the conjunctiva astride the limbus?

Which one will not penetrate the cornea and shows up as a small, yellowish submucosal elevation?

A
  1. Pterygium

2. Pinguecula

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10
Q

Which structure is the major refractive surface of the eye?

A

Cornea (NOT the lens)

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11
Q

________ is an example of a condition that destroys the contour of the cornea and alters its refractive surface.

A

Keratoconus

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12
Q

Corneal dystrophies are typically _________, while corneal degenerations are typically ________ .

A
  1. Inherited

2. Not inherited

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13
Q

Describe the anatomy of the anterior segment.

A

The anterior chamber is bound anteriorly by the cornea, laterally by the trabecular meshwork and porsteriorly by the iris

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14
Q

________ describes lenticular opacities that may be congenital or acquired.

A

Cataract

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15
Q

Which part of the eye is going to contain cataracts?

A

Lens

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16
Q

Advanced age, smoking, sun exposure, atopic dermatitis, Diabetes mellitus, Wilson disease, Galactosemia and certain drugs are all risk factors for ___________ .

A

Developing Cataracts

17
Q

Age, Race, Family History, Diabetes, Trauma, Prolonged corticosteroid use and eye abnormalities are all risk factors for __________ .

A

Glaucoma

18
Q

In ___________ , the aqueous humor has complete physical access to the trabecular meshwork, and the elevation in intraocular pressure results from an increased resistance to aqueous outflow.

A

Open-angle Glaucoma

19
Q

In _______. the peripheral zone of the iris adheres to the trabecular meshwork and physically impedes the egress of aqueous humor from the eye.

A

Angle-closure Glaucoma

20
Q

__________ glaucoma typically develops in eyes with shallow anterior chambers, often found in individuals with hyperopia.

A

Primary Angle-closure

21
Q

__________ glaucoma has many causes.

A

Secondary Angle-closure

22
Q

_______ is an example of a systemic condition that may produce granulomatous uveitis and sympathetic opthalmia may produce bilateral granulomatous inflammation as a possible consequence of penetrating injury to one eye.

A

Sarcoid

23
Q

The most common intraocular tumor of adults is _________ to the eye.

A

Metastasis

24
Q

The most common primary intraocular timor of adults is ____________ .

A

Uveal melanoma

25
Q

Where is the first evidence of uveal melanoma typically spotted?

A

Liver

26
Q

Mutations in MYOC (myoclilin) genes have been associated with _________ primary open-angle glaucoma.

A

Juvenile

27
Q

Mutations in OPTN (optineurin) genes have been associated with ________ primary open-angle glaucoma.

A

Adult

28
Q

________ is a term used to describe inflammation of the interior of the eye involving the vitreous humor.

A

Endophthalmitis

29
Q

________ is the term used to describe inflammation of the interior of the eye that also extends into the uvea and sclera.

A

Panophthalmitis

30
Q

Which three anatomical structures make up the uvea?

A
  1. Iris
  2. Choroid
  3. Ciliary Body
31
Q

__________ retinal detachment is associated with a full-thickness retinal defect.

A

Rhegmatogenous

32
Q

_________ is retinal detachment without a retinal break.

A

Non-rhegmatogenous

33
Q

Malignant Hypertension and Choroidal tumors are examples of _________ retinal detachment.

A

Non-rhegmatogenous

34
Q

In ________, blood vessels in the eye may appear narrowed, and the color of the blood column may change from bright red to copper and to silver depending on the degree of vascular wall thickness.

A

Retinal arteriolosclerosis

35
Q

Thickening of the basement membrane of the epithelium of the pars plicata of the ciliary body is a reliable histological marker for _______.

A

Diabetes Mellitus

36
Q

Tay-Sachs and Nieman-Picks disease both have which common eye pathology?

A

Cherry Red Spot