pulomonary medications Flashcards
what effects the bronchi and bronchioles
bronchcocontriciton
what plays a major role in the pathophysiology of most obstructive respiratory disorders
bronchocontrition
what is the balance of sympathetic and parasympathetic input to the smooth mm of brochi and bronchioles
bronchomotor tone q
what are the 3 main causes of abnormal bronchomotor tone
inflammation
excessive PNS activity
reduces SNS activity
bronchodilators act as ____ agents
sympathomimetics agents
(medications that mimic the SNS)
what are sympathomimetics agents (bronchiodilators) used for
anaphylaxis and acute asthma
what is used for lower respiratory disorders
sympathomimetics agents (bronchiodilators)
what drug is used during acute phase of asthmatic attacks
sympathomimetics agents (bronchiodilators)
what does sympathomimetics agents (bronchodilators) stimulate throughout the lungs
beta 2 adrenergic receptors
what drug is a sympathomimetics agent that works in 3-5 mins and effects last for 4-6 hours and acts as a rescue inhaler
short acting beta 2 agonist (SABA)
what sympathomimetics agents is given in emergent situation and what does it effect
epinephrine and affects all a drenergic receptors
why is epinephrine given in emergency situation
to promote bronchodilation and increase BP
what are some side effects of epinephrine (sympathomimetic agents)
tremors , dizziness , HTN , tachycardia , heart palapitation and angina
if someone has bronchospasm due to COPD what drug are they given via aerosol or tablet
selective beta2 adenergic agonist
what are 3 examples of selective beta 2 adrenergic agonist that are giving to patients with bronchospasm due to COPD
albuterol , salbutamol (SABA
formoterol (FABA)
salmeterol (FABA)
what drug is given to a patients with bronchospasm due to COPD with the effects beginning within 2-20 min , works up to 12 hours , used to help COPD pateints slow and used for matienance therapy
long lasting beta 2 agonist
what are some adverse reactions related to SABA
cough
tachycardia
muscle tremor
muscle contractions
what stimulate alpha-adrenergic receptor vasoconstriction of capillaries w/in nasal mucosa
shrinking of the nasal mucus membranes & reduction in fluid secretion (runny nose)
decongestants
decongestants can lead to __ in BP bc of vasoconstriction in the gut area
increase
what are side effects of decongestants
dizziness
hypertension
headaches
nausea
nervousness
insomnia
cardiovascular irregularities
what is used with anti inflammatories to treat acute moderate to severe asthma
parasympatholytics
parasympatholytics meds facilitates ____
bronchodilation
what affects the nicotinic and muscarinic receptors
acteylocholine
what are 2 muscarinic antagonist ?
ipratropium (atrovent) SAMA
tiotropium (spiriva) LAMA
what does atropine do
promote bronchodilation and decreased mucus secretions
what is used for paralysis of the respiratory system due to poisoning
atropine
is atropine used for asthma
no
what are the 8 side effects of atropine
dry mouth
headaches
tachycardia
blurred vison
rash
decreased GI activity
dizziness
confusion
what is an enzyme that reduces intracellular levels of cAMP
phosphodiesterase (PDE)
what promotes an increase in cAMP by blocking the breakdown of cAMP
methylxanthines
what is the precursor to norepinephrine and epinephrine
cAMP