pulmonary infectious disorders Flashcards

1
Q

What is included with the pulmonary microbiome

A

preveotella
veilonella
streptococcus

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2
Q

What is pneumonia

A

infection within the lung tissue

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3
Q

How is pneumonia spread

A

inhilation
hematogenous
aspiration

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4
Q

Who is at higher risk for aspiration pneumonia

A

Patients with a decreased cough reflex

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5
Q

What is the most common cause of increased bacterial load within the lungs

A

microaspiration

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6
Q

What is the most common bacterial cause of pneumonia

A

strep pneumonia
H. influenza
mycoplasma pneumonia

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7
Q

Which type of pneumonia is associated with otitis media and pharyngitis

A

Mycoplasma pneumonia

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8
Q

what is the structure of mycobacteria

A

thick lipid cell wall that creates a waxy layer

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9
Q

What does the waxy layer on mycobacteria allow for

A

allows for bacteria to form granulomas

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10
Q

How is TB transmitted

A

aerosolized droplets

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11
Q

When does a TB test become positive after exposure

A

3 weeks

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12
Q

How does the body react to TB inhalation

A

Will phagocytize the bacteria and form a chronic granuloma to encase the infection

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13
Q

Clinical presentation of TB

A

Cough
hemoptysis
pleuritic pain
night sweats
weight loss
fatigue

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14
Q

What are the stages of TB

A

Primary TB
Progressive primary TB
Latent phase
Reactivation

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15
Q

When does primary TB occur

A

Initial symptoms post exposure (roughly 3 weeks)

Granuloma is formed and caseous necrosis happens

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16
Q

What is progressive primary TB

A

New TB infection or newly active disease

may be asymptomatic

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17
Q

What is the reactivation phase of TB

A

this is the stage where the classic symptoms present

18
Q

How do you test for TB

A

Acid fast stain

19
Q

What is extra pulmonary TB

A

milliary TB: bacteremic infection that spreads to other tissues

20
Q

How does TB typically spread within the body and to where

A

Primary via lymphatics and primarily to the lung apices

21
Q

What is bronchitis

A

inflammatory response in the lower respiratory tract

22
Q

What generally causes bronchitis

23
Q

Who is bronchiolitis most common in

24
Q

What is the most common viral cause of bronchiolitis

25
What is the most common organism for epiglottitis
S aureus S pneumonia
26
What viral causes can cause epiglottitis
Flu Herpes EBV HIV
27
What factors outside of infections that can cause epiglottitis
Thermal burns trauma
28
What sound will occur when someone has epiglottitis
Stridor
29
Will inflammation from epiglottitis travel inferior to the vocal cords?
no
30
What is the epiglottitis triad
Drooling Dysphagia Distress
31
What is pertussis
Aerobic, gram negative with no known animal reservoirs
32
What is pertussis virulence factors
They encourage attachment to ciliated epithelial cells within the trachea and bronchi
33
What is pertussis toxin
Assists with binding and gaining entry into the epithelial cells
34
What does the pertussis toxin cause
histamine sensitization increased insulin synthesis
35
What is Filamentous hemagglutinin
Surface protein pili that will help with adhesiveness
36
What do pertussis surface proteins help with
Allows for velcro effect to epithelial cells and erythrocytes
37
What does cytoplasmic adenylate cyclase do
impairs chemotaxis and weakens phagocytosis of host cells
38
What is tracheal cytotoxin
Destroys ciliated epithelial cells Body becomes unable to clear mucus and bacteria
39
How is pertussis transmitted
Inhalation or respiratory droplets
40
What does pertussis toxin bind to
any mammalian cell and modulates a host immune response
41
What is another name for pertussis
whooping cough
42
What are the stages of whooping cough
catarrhal stage (1-2wks) *pt most contagious in this stage Paroxysmal stage *cough becomes very prominent, vomiting an hypoxia are common Convalescent stage *pt. no longer contagious