Pulmonary Drugs and Diuretics

Question 1

Mannitol

Answer 1

Osmotic diuretic
Works in PCT and descending loop of Henle
Treats increases in intracranial pressure

Question 2

Urea

Answer 2

Osmotic diuretic
Works in PCT and descending limb
Treats increases in intracranial pressure

Question 3

Acetazolamide

Answer 3

Carbonic anhydrase inhibitor
Work in PCT
Treats glaucoma and mountain sickness

Question 4

Furosemide

Answer 4

Loop diuretic

Works in the ascending limb

Question 5

Bumetanide

Answer 5

Loop diuretic

Works in the ascending limb

Question 6

Torsemide

Answer 6

Loop diuretic

Works in the ascending limb

Question 7

Ethacrynic acid

Answer 7

Loop diuretic

Works in the ascending limb

Question 8

Chlorothiazide

Answer 8

Thiazide diuretic

Works in the DCT

Question 9

Hydrochlorothiazide

Answer 9

Thiazide diuretic

Works in the DCT

Question 10

Chlorthalidone

Answer 10

Thiazide-like diuretic

Works in DCT

Question 11

Indapamide

Answer 11

Thiazide-like diuretic

Works in DCT

Question 12

Metolazone

Answer 12

Thiazide-like diuretic

Works in DCT

Question 13

Spironolactone

Answer 13

Potassium-sparing diuretic
Inhibits aldosterone-receptor complex
Works in intercalated cells of the collecting duct
Good for resistant HTN

Question 14

Eplerenone

Answer 14

Potassium-sparing diuretic
Inhibits aldosterone-receptor complex
Works in intercalated cells of the collecting duct
Good for resistant HTN

Question 15

Triamterene

Answer 15

Potassium-sparing diuretic

Blocks sodium transport channels in principle cells of the collecting duct

Question 16

Amiloride

Answer 16

Potassium-sparing diuretic

Blocks sodium transport channels in principle cells of the collecting duct

Question 17

Albuterol

Answer 17

Short acting beta-2 agonist

Question 18

Terbutaline

Answer 18

Short acting beta-2 agonist

Question 19

Metaproterenol

Answer 19

Short acting beta-2 agonist

Question 20

Bitolterol

Answer 20

Short acting beta-2 agonist

Question 21

levalbuterol

Answer 21

Short acting beta-2 agonist

Question 22

Salmeterol

Answer 22

Long acting beta-2 agonist

Question 23

Formoterol

Answer 23

Long acting beta-2 agonist

Question 24

Atropine

Answer 24

Muscarinic antagonist (anticholinergic)
Blocks M3 receptor
Good for patients who can’t tolerate a SABA or has COPD

Question 25

Ipratropium

Answer 25

Short acting muscarinic antagonist (anticholinergic) Blocks M3 receptor Good for patients who can't tolerate a SABA or has COPD

Question 26

Tiotropium

Answer 26

Long acting muscarinic antagonist (anticholinergic) Blocks M3 receptor Good for patients who can't tolerate a SABA or has COPD

Question 27

Theophylline/aminophylline

Answer 27

Methylxanthines | Blocks adenosine A2 receptor and prevents phosphodiesterase from breaking down cAMP

Question 28

Prednisone

Answer 28

Oral corticosteroid | Inhibit phospholipase A2

Question 29

Beclomethasone

Answer 29

Inhaled corticosteroid | Inhibit phospholipase A2

Question 30

Budesonide

Answer 30

Inhaled corticosteroid | Inhibit phospholipase A2

Question 31

Fluticasone

Answer 31

Inhaled corticosteroid | Inhibit phospholipase A2

Question 32

Mometasone

Answer 32

Inhaled corticosteroid | Inhibit phospholipase A2

Question 33

Flunisolide

Answer 33

Inhaled corticosteroid | Inhibit phospholipase A2

Question 34

Ciclesonide

Answer 34

Inhaled corticosteroid | Inhibit phospholipase A2

Question 35

Zileuton

Answer 35

Leukotriene modifier | Inhibits 5-lipoxgenase

Question 36

Montelukast

Answer 36

Leukotriene modifier | Inhibits LTD4 receptor

Question 37

Zafirlukast

Answer 37

Leukotriene modifier | Inhibits LTD4 receptor

Question 38

Omalizumab

Answer 38

Monoclonal antibody binds to IgE to prevent interaction with mast cells

Question 39

Cromolyn

Answer 39

Inhibits mast cell degranulation

Question 40

Nedocromil

Answer 40

Inhibits mast cell degranulation

Question 41

Roflumilast

Answer 41

Phosphodiesterase-4 inhibitor | Treats COPD

Question 42

Bupropion

Answer 42

Dopaminergic-noradrenergic reuptake inhibitor | Good for smoking cessation

Question 43

Varenicline

Answer 43

Nicotine receptor agonist | Good for smoking cessation