Pulmonary Drugs and Diuretics Flashcards

1
Q

Mannitol

A

Osmotic diuretic
Works in PCT and descending loop of Henle
Treats increases in intracranial pressure

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2
Q

Urea

A

Osmotic diuretic
Works in PCT and descending limb
Treats increases in intracranial pressure

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3
Q

Acetazolamide

A

Carbonic anhydrase inhibitor
Work in PCT
Treats glaucoma and mountain sickness

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4
Q

Furosemide

A

Loop diuretic

Works in the ascending limb

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5
Q

Bumetanide

A

Loop diuretic

Works in the ascending limb

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6
Q

Torsemide

A

Loop diuretic

Works in the ascending limb

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7
Q

Ethacrynic acid

A

Loop diuretic

Works in the ascending limb

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8
Q

Chlorothiazide

A

Thiazide diuretic

Works in the DCT

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9
Q

Hydrochlorothiazide

A

Thiazide diuretic

Works in the DCT

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10
Q

Chlorthalidone

A

Thiazide-like diuretic

Works in DCT

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11
Q

Indapamide

A

Thiazide-like diuretic

Works in DCT

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12
Q

Metolazone

A

Thiazide-like diuretic

Works in DCT

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13
Q

Spironolactone

A

Potassium-sparing diuretic
Inhibits aldosterone-receptor complex
Works in intercalated cells of the collecting duct
Good for resistant HTN

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14
Q

Eplerenone

A

Potassium-sparing diuretic
Inhibits aldosterone-receptor complex
Works in intercalated cells of the collecting duct
Good for resistant HTN

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15
Q

Triamterene

A

Potassium-sparing diuretic

Blocks sodium transport channels in principle cells of the collecting duct

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16
Q

Amiloride

A

Potassium-sparing diuretic

Blocks sodium transport channels in principle cells of the collecting duct

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17
Q

Albuterol

A

Short acting beta-2 agonist

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18
Q

Terbutaline

A

Short acting beta-2 agonist

19
Q

Metaproterenol

A

Short acting beta-2 agonist

20
Q

Bitolterol

A

Short acting beta-2 agonist

21
Q

levalbuterol

A

Short acting beta-2 agonist

22
Q

Salmeterol

A

Long acting beta-2 agonist

23
Q

Formoterol

A

Long acting beta-2 agonist

24
Q

Atropine

A

Muscarinic antagonist (anticholinergic)
Blocks M3 receptor
Good for patients who can’t tolerate a SABA or has COPD

25
Q

Ipratropium

A

Short acting muscarinic antagonist (anticholinergic)
Blocks M3 receptor
Good for patients who can’t tolerate a SABA or has COPD

26
Q

Tiotropium

A

Long acting muscarinic antagonist (anticholinergic)
Blocks M3 receptor
Good for patients who can’t tolerate a SABA or has COPD

27
Q

Theophylline/aminophylline

A

Methylxanthines

Blocks adenosine A2 receptor and prevents phosphodiesterase from breaking down cAMP

28
Q

Prednisone

A

Oral corticosteroid

Inhibit phospholipase A2

29
Q

Beclomethasone

A

Inhaled corticosteroid

Inhibit phospholipase A2

30
Q

Budesonide

A

Inhaled corticosteroid

Inhibit phospholipase A2

31
Q

Fluticasone

A

Inhaled corticosteroid

Inhibit phospholipase A2

32
Q

Mometasone

A

Inhaled corticosteroid

Inhibit phospholipase A2

33
Q

Flunisolide

A

Inhaled corticosteroid

Inhibit phospholipase A2

34
Q

Ciclesonide

A

Inhaled corticosteroid

Inhibit phospholipase A2

35
Q

Zileuton

A

Leukotriene modifier

Inhibits 5-lipoxgenase

36
Q

Montelukast

A

Leukotriene modifier

Inhibits LTD4 receptor

37
Q

Zafirlukast

A

Leukotriene modifier

Inhibits LTD4 receptor

38
Q

Omalizumab

A

Monoclonal antibody binds to IgE to prevent interaction with mast cells

39
Q

Cromolyn

A

Inhibits mast cell degranulation

40
Q

Nedocromil

A

Inhibits mast cell degranulation

41
Q

Roflumilast

A

Phosphodiesterase-4 inhibitor

Treats COPD

42
Q

Bupropion

A

Dopaminergic-noradrenergic reuptake inhibitor

Good for smoking cessation

43
Q

Varenicline

A

Nicotine receptor agonist

Good for smoking cessation