Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > CNS Drugs, Part II > Flashcards

CNS Drugs, Part II Flashcards

1
Q

Clonazepam

A

Long-acting benzodiazepine

Good for treating seizures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Lorazepam

A

Intermediate-acting benzodiazepine
Good for terminating status epilepticus
Good for alcohol withdrawal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Diazepam

A

Long-acting benzodiazepine
Good for terminating status epilepticus
Good for alcohol withdrawal
Good for skeletal muscular spasms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Alprazolam

A

Short and long-term benzodiazepine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Temazepam

A

Intermediate-acting benzodiazepine

Good for sleep disorders with frequent waking

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Triazolam

A

Short-acting benzodiazepine

Good for sleep disorders with difficulty falling asleep

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Midazolam

A

Benzodiazepine

Good for amnesia and sedation prior to anesthesia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Chlordiazepoxide

A

Long-acting benzodiazepine

Good for alcohol withdrawal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Chlorazepate

A

Long-acting benzodiazepine

Good for alcohol withdrawal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Etazolam

A

Intermediate-acting benzodiazepine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Flurazepam

A

Long-acting benzodiazepine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Oxazepam

A

Short-acting benzodiazepine

Good for alcohol withdrawal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Quazepam

A

Long-acting benzodiazepine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Flumazenil

A

Benzodiazepine/GABA receptor antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Baclofen

A

Muscle relaxant

Spinal cord GABAb receptor agonist –> inhibits glutamate neurotransmitter release

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Thiopental

A

Ultra short-acting barbiturate

Can induce anesthesia (IV)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Phenobarbital

A

Long-acting barbiurate
Anti-convulsant –> treats focal and tonic-clonic seizures
Treats refractory status epilepticus
Avoid in children –> depresses cognitive development

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Pentobarbital

A

Short-acting barbiturate

Can also block high-frequency sodium channels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Secobarbital

A

Short-acting barbiturate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Amobarbital

A

Short-acting barbiturate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Butalbital

A

Short-acting barbiturate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Buspirone

A

Anxiolytic

Serotonin and dopamine receptor activity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Zolpidem

A

Hypnotic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Zaleplon

A

Hypnotic

Helps with sleep maintenance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Eszopiclone

A

Hypnotic

Approved for long-term use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Ramelteon

A

Hypnotic
Agonist of MT1 and MT2 receptors (melatonin)
Treats insomnia with difficulty falling asleep
Increases prolactin levels
Approved for long-term use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Paroxetine

A

SSRI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Escitalopram

A

SSRI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Venlafaxine

A

SNRI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Duloxetine

A

SNRI

31
Q

γ-Hydroxybutyrate (GHB)/Sodium oxybate

A

GABA precursor

Treats cataplexy and narcolepsy

32
Q

Tizanidine

A

Muscle relaxant

33
Q

Dantrolene

A

Muscle relaxant
Decreases calcium release from SR
Used to treat malignant hyperthermia

34
Q

Ethosuximide

A

Epilepsy drug
Treats absence seizures
Blocks thalamic T-type calcium channels

35
Q

Phenytoin

A

Epilepsy drug
Treats focal, generalized, and absense seizures
Blocks voltage-gated sodium channels
Side effects: gingival hyperplasia, nystagmus, ataxia, hirsutism, SJS
Contraindicated in pregnancy

36
Q

Carbamazepine

A

Epilepsy drug
Treats focal and generalized seizures, trigeminal neuralgia, bipolar disorder
Blocks sodium channels
Side effects: hyponatremia, SJS
Contraindicated for pregnancy and absence seizures

37
Q

Valproic acid

A

Epilepsy drug
Treats focal, generalized, and absence seizures, bipolar disorder
Blocks sodium channels, GABA transaminase
Side effects: hepatotoxicity
Contraindicated in pregnancy

38
Q

Gabapentin

A

Epilepsy drug
Treats partial and generalized seizures, peripheral neuropathy, postherpetic neuralgia
GABA analog that inhibits voltage-gated calcium channels

39
Q

Topiramate

A

Epilepsy drug
Treats focal and generalized seizures and migraine
Blocks voltage-gated sodium and calcium channels

40
Q

Lamotrigine

A

Epilepsy drug
Treats focal, generalized, and absence seizures
Blocks sodium and calcium channels
Side effects: SJS

41
Q

Levetiracetam

A

Epilepsy drug
Treats focal and generalized seizure
May modulate GABA and glutamate release by binding to synaptic vesicle protein

42
Q

Tiagabine

A

Epilepsy drug
Treats focal seizures
Inhibits GABA reuptake

43
Q

Vigabatrin

A

Epilepsy drug
Treats focal seizures
Irreversibly inhibits GABA transaminase
Side effects include vision loss

44
Q

Sumatriptan

A

Triptan
Aborts or reduces the severity of migraine headache
Agonist of serotonin 5-HT1D receptors
Contraindicated in patients with CVD risk factors

45
Q

Ergotamine

A

Ergot alkaloid
Aborts migraine headaches
Agonist of serotonin 5-HT1 receptors –> vasoconstriction
Contraindicated in angina, PVD, and pregnancy

46
Q

Dihydroergotamine

A

Ergot alkaloid
Aborts migraine headaches
Agonist of serotonin 5-HT1 receptors –> vasoconstriction
Contraindicated in angina, PVD, and pregnancy

47
Q

Levodopa

A

Dopamine precursor to treat Parkinson’s

Coadministered with carbidopa and entacopone

48
Q

Selegiline

A

MAO type B inhibitor

Treats Parkinson’s, depression

49
Q

Rasagiline

A

Irreversible inhibitor of MAO type B

Treats Parkinson’s, depression

50
Q

Bromocriptine

A

Ergot derivative; D2 agonist
Treats Parkinson’s
Reduced risk for dyskinesia
Contraindicated for Hx of MI, PAD

51
Q

Ropinirole

A

Non-ergot D2 agonist
Treats Parkinson’s
Reduced risk for dyskinesia

52
Q

Pramipexole

A

Non-ergot D2 agonist
Treats Parkinson’s
Reduced risk for dyskinesia

53
Q

Rotigotine

A

Non-ergot D2 agonist
Treats Parkinson’s
Reduced risk for dyskinesia

54
Q

Apomorphine

A

Non-ergot D2 agonist
Treats Parkinson’s
Reduced risk for dyskinesia

55
Q

Amantidine

A

NMDA glutamate receptor inhibitor

Treats Parkinson’s

56
Q

Benzotropine

A

Antimuscarinic agent
Treats Parkinson’s
Contraindicated for glaucoma, prostatic hyperplasia, pyloric stenosis

57
Q

Trihexyphenidyl

A

Antimuscarinic agent
Treats Parkinson’s
Contraindicated for glaucoma, prostatic hyperplasia, pyloric stenosis

58
Q

Donepezil

A

Acetylcholinesterase inhibitor

Treats Alzheimer’s

59
Q

Galantamine

A

Acetylcholinesterase inhibitor

Treats Alzheimer’s

60
Q

Rivastigmine

A

Acetylcholinesterase inhibitor

Treats Alzheimer’s and dementia associated with Parkinson’s

61
Q

Memantine

A

NMDA glutamate receptor antagonist
Treats Alzheimer’s
Coadministered with AChE inhibitor

62
Q

Haloperidol

A

Typical antipsychotic

Treats schizophrenia and tic disorder

63
Q

Chlorpromazine

A

Typical antipsychotic

Treats schizophrenia, intractable hiccups, and mania

64
Q

Clozapine

A

Atypical antipsychotic
Treats schizophrenia and improves cognitive function
Side effects: agranulocytosis

65
Q

Risperidone

A

Atypical antipsychotic

Treats schizophrenia, tic disorder, autism-related disruptive behavior, and mania

66
Q

Olazapine

A 
Atypical antipsychotic
Treats schizophrenia (improves cognitive function) and bipolar disorder (with SSRI)
67
Q

Quetiapine

A

Atypical antipsychotic

Treats schizophrenia, bipolar disorder, and refractory depression

68
Q

Ziprasidone

A

Atypical antipsychotic
Treats schizophrenia and mania
Causes the least weight gain

69
Q

Aripiprazole

A

Dopamine system stabilizer

Treats schizophrenia, bipolar disorder, and autistic diorder

70
Q

D-amphetamine

A

CNS stimulant
Treats ADHD and narcolepsy
Displaces monoamines

71
Q

Methyphenidate

A

CNS stimulant
Treats ADHD and narcolepsy
Inhibits reuptake of NE and DA

72
Q

Atomoxetine

A

CNS stimulant
Treats ADHD
Prevents reuptake of NE

73
Q

Modafinil

A

CNS stimulant
Treats narcolepsy
Inhibits reuptake of NE and DA, increases free serotonin, decreases GABA

74
Q

Cocaine

A

CNS stimulant

Blocks reuptake of DA, NE, 5HT

Pharmacology (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions