Pulmonary Drugs

Question 1

Albuterol (small animal) and Clenbuterol (horse)

Answer 1

• beta2 adrenergic agonists
• results in increased diameter of small and large airways
• increased mucociliary clearance
• decreased release of inflammatory mediators

Question 2

Theophylline

Answer 2

• inhibits phosphodiesterase activity leading to decreased cAMP breakdown
• results in dilation of large and small airways
• increased mucociliary clearance
• anti-inflammatory effects

Question 3

Atropine, Glycopyrrolate, and Ipratropium

Answer 3

• block muscarinic receptors

- results in bronchodilation

Question 4

Dextromethorphan

Answer 4

• agonist at sigma receptors but mechanism of action is uncertain
• antitussive agent

Question 5

Butorphanol

Answer 5

• agonist of kappa opioid receptors

- antitussive agent