Catecholaminergic Drugs Flashcards
1
Q
Phenylephrine
A
- alpha1 AR agonist
- causes arteriolar and venous constriction
- increased systolic and diastolic pressure
- reflex decrease in HR
- pupillary dilation
2
Q
Medetomidine and Xylazine
A
- alpha1 AR agonist
- sedative
- muscle relaxant
- analgesic affects
- (xylazine produces vomiting in cats)
3
Q
Phentolamine
A
- non-specific alpha AR antagonist
- decreased peripheral resistance
- decreased blood pressure
- tachycardia
- arrhythmias
- pain
- nausea
- increased gastric acid secretion
4
Q
Prazosin
A
- alpha1 AR antagonist
- relaxation of vascular smooth muscle
- decreased peripheral resistance
- decreased venous return to heart
- decreased cardiac preload
5
Q
Atipamezol and Yohimbine
A
- alpha2 AR antagonist
- inhibits analgesic, muscle relaxant, and sedating effects of centrally acting alpha2 AR agonists
- (used to reverse CNS and cardiovascular depression in dogs)
6
Q
Isoproterenol
A
- non-specific beta AR agonist
- increases systolic blood pressure but decreases diastolic blood pressure
- bronchodilation
- alleviates cardiac AV block
7
Q
Ractopamine
A
- non-specific beta AR agonist
- used in livestock feed to boost lean meat yield by altering nutrient metabolism
8
Q
Dobutamine
A
- beta1 AR agonist
- increases cardiac contractility
- increases heart rate
9
Q
Albuterol and Clenbuterol
A
- beta2 AR agonist
- relaxbronchial, uterine, and vascular smooth muscle
10
Q
Propanolol
A
- non-specific beta AR antagonist
- decreased heart rate
- decreased cardiac contractility
- blocks effects of NE on AV node
11
Q
Atenolol, Betaxolol, and Esmolol
A
- beta1 AR antagonist
- negative inotropic and chronotropic effects
