PTSD Flashcards

1
Q

True/False: PTSD is a normal event that happens after a traumatic event

A

False. It is an anxiety disorder that follows a traumatic event and is debilitating to those it affects

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2
Q

Risk factors for developing PTSD

A

Woman - more sx and longer duration
Events involving masses of people
Sudden/unexpected loss of a loved one

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3
Q

Three Core Sx of PTSD and how many of each is needed for dx

A

Re-experiencing: 1
Avoidance: 3
Arousal: 2

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4
Q

What is required in the DSM-IV of the event?

A

Experienced/witnessed by patient
In real danger of death/injury
Response was fear, horror, etc

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5
Q

How long do sx have to cause distress/impairment until before being able to be diagnosed?

A

1 month

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6
Q

Explain the difference between acute, chronic and delayed onset PTSD

A

Acute <3 months
Chronic ≥3 months
Delayed onset not seeing sx until at least 6 months after the event

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7
Q

Comorbid Disease State Considerations

A
MDD
Anxiety
Substance Abuse
Sleep disorders
Suicidal Ideation
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7
Q

Comorbid Disease State Considerations

A
MDD
Anxiety
Substance Abuse
Sleep disorders
Suicidal Ideation
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8
Q

First Line

A
SSRI
Helps with: sleep, nightmares, re-experiencing
Does not help with: Avoidance sx
Dosing: Start low and go slow
Adequate trial length: 6-8 weeks
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8
Q

First Line

A
SSRI
Helps with: sleep, nightmares, re-experiencing
Does not help with: Avoidance sx
Dosing: Start low and go slow
Adequate trial length: 6-8 weeks
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9
Q

Which SSRI do we avoid and why?

A

Paxil
Lots of Anti-Ach - hypotension
Weight gain

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9
Q

Which SSRI do we avoid and why?

A

Paxil
Lots of Anti-Ach - hypotension
Weight gain

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10
Q

What side effects are most common?

A

GI upset when initiating and changing dose

Sexual dysfunction

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10
Q

What side effects are most common?

A

GI upset when initiating and changing dose

Sexual dysfunction

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11
Q

What side effects are rarer and more serious?

A

GI bleed
SR syndrome
SIADH

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11
Q

What side effects are rarer and more serious?

A

GI bleed
SR syndrome
SIADH

12
Q

2nd Line

A

SNRI
Helps with: PTSD and 2˚ pain
Dosing: ER formulation ONLY
Adequate trial length: 6-8 weeks

12
Q

2nd Line

A

SNRI
Helps with: PTSD and 2˚ pain
Dosing: ER formulation ONLY
Adequate trial length: 6-8 weeks

13
Q

What SNRI side effects are most common?

A
GI upset
Headache
Agitation
Insomnia
Sexual dysfunction
13
Q

What SNRI side effects are most common?

A
GI upset
Headache
Agitation
Insomnia
Sexual dysfunction
14
Q

Which SNRI AEs are rarer and more serious?

A

SR syndrome

GI bleed

14
Q

Which SNRI AEs are rarer and more serious?

A

SR syndrome

GI bleed

15
Q

Which medications have the worst d/c syndrome?

A

Paxil and Effexor

15
Q

Which medications have the worst d/c syndrome?

A

Paxil and Effexor

16
Q

Third Line

A

Phenelzine (MAOi)

Remeron

16
Q

Third Line

A

Phenelzine (MAOi)

Remeron

17
Q

Adjunct or 1˚ Treatment for Nightmares in PTSD

A

Name: Prazosin
MOA: alpha 1 blocker
Why this over other in same class? Crosses BBB
Clinical effect: Reduces night terrors, more REM sleep
Dosing: Start at 1mg at bedtime and titrate based on ADRs and effect
Monitoring: Orthostatic hypotension

17
Q

Adjunct or 1˚ Treatment for Nightmares in PTSD

A

Name: Prazosin
MOA: alpha 1 blocker
Why this over other in same class? Crosses BBB
Clinical effect: Reduces night terrors, more REM sleep
Dosing: Start at 1mg at bedtime and titrate based on ADRs and effect
Monitoring: Orthostatic hypotension

18
Q

What do we avoid in PTSD?

A

BZDs

TCAs

18
Q

What do we avoid in PTSD?

A

BZDs

TCAs