PTA Flashcards
What are the different forms of Asthma?
- Allergic
- Non-allergic (exercise induced etc)
- Late onset asthma (in adult life)
- With fixed air flow limitation (due to airway remodelling)
- With obesity
How many people in NL suffer from Asthma?
1.8 million
Is Asthma more prevalent in men or women?
Women
What does IgE in Asthma stand for?
Immunoglobulin E
(an antibody generated by the immune system in response to a harmless stimulus)
What happens during the first contact with an allergen in Asthma?
- IgE production by eusoniphil leucocytes starts
- IgE attaches to mast cell
→ No symptoms
What happens during the second contact with an allergen in Asthma?
- Allergen binds to IgE molecules (which are now attached to mast cell)
- Mast cell gets activated/degranulated
- Histamine is released → causes allergic reaction
What are the characteristics of a non-allergic asthmatic reaction?
- Non-specific stimulus like effort, smoke, dust, fog, cold, viral infection, stress is present
- Degranulation of mast cell and release of histamine without involvement of IgE
Exercise-induced bronchoconstriction is the case in?
Exercise induced asthma
What can absence of wheezing in asthma patients indicate?
Exacerbation! Silent chest
How can asthma best be treated?
Minimising future risk of:
- Exacerbation
- Fixed airflow limitation
- Side-effects of medication
- Immediately decreased risk of cardiorespiratory problems by 50%
- Decrease of cholesterol after 1 week
- Decrease of blood pressure by 10mmHg
- Decrease of pulse by 10-25 bpm
- Decreased risk of infection
- Decrease in adrenaline production
These are benefits of eliminating which risk factor?
Smoking
The risk for cardiac pathology equals non-smokers when?
2-3 years after quitting smoking
Cholesterol decrease of 10% lowers the risk of cardiac pathology by?
20%
Total cholesterol should be?
190mg/dL or 5mmol/L or below
LDL should be?
150mg/dL or 3,9mmol/L or below
HDL should be?
At least 45mg/dL or 1mmol/L
What are benefits of a normal blood pressure?
- Decreased risk of cardiovascular pathology
- Decreased risk of kidney problems
- Decreased risk of stroke
- Decreased load on the heart
Goals of cardiac rehab are?
→ Prevention / treatment of pulmonary complications
→ Treatment of risk factors
→ Improve and maintain exercise capacity
→ Improve quality of life
What are the phases of cardiac rehab?
- Preoperative phase
- Phase 1 or clinical phase
- Phase 2 or rehabilitation phase
- Phase 3 or post-rehabilitation phase
When does the preoperative phase of cardiac rehab start?
4 weeks before surgery
What is the frequency and duration of sessions in the preoperative phase of cardiac rehab?
7 days per week
20min per session
What aspects are trained in the preoperative phase of cardiac rehab?
- Inspiratory muscle training (IMT) with threshold device
- Breathing exercises
- Airway clearance techniques
Which patients have to do the preoperative phase of cardiac rehab?
Open heart surgery patients
(coronary artery bypass grafting CABG and/or valve replacement)
→ with increased risk of developing pulmonary complications post-operative
When does phase 1/clinical phase of cardiac rehab start?
Immediately after acute cardiac event