Anatomy Flashcards

1
Q

What is the RCA and where does it lie?

A

Right coronary artery

→ Originates from ascending aorta (more anteriorly)

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2
Q

What does the RCA innervate?

A

Posterior heart wall together with ramus circumflex/circumflex artery of LCA

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3
Q

What is the LCA and where does it lie?

A

Left coronary artery

→ Originates from ascending aorta (more posteriorly)

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4
Q

Why can necrosis easily occur once a coronary artery is blocked?

A

There is no collateral circulation and arteries end in the muscle

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5
Q

What is a different term for pericardium?

A

Heart pocket

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6
Q

What are functions of the pericardium?

A
  • Protects against blows to the heart
  • Avoids friction when heart moves/pumps
  • Prevents overstretching of muscle fibres
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7
Q

What are the layers of the pericardium from superficial to deep?

A

→ Fibrous pericardium
→ Parietal layer
→ Pericardial cavity

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8
Q

What happens in case of a pericarditis?

A

→ Inflammation and swelling will minimise room for myocardium to pump and function

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9
Q

What are the layers of the myocardium from superficial to deep?

A

Epicardium (visceral layer of serous pericardium)
Myocardium
Endocardium

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10
Q

Which organ is innervated by the hepatic artery and vein?

A

The liver

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11
Q

Which organ is innervated by the renal artery and vein?

A

The kidneys

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12
Q

Which vein connects the stomach and intestines with the liver?

A

The hepatic portal vein

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13
Q
  • Small lumen
  • Situated deeper in tissue
  • Only valves at base of aorta and pulmonary arteries
  • High pressure
  • Pulse palpable
  • Thick elastic wall
    → Outer layer CT
    → Middle layer smooth muscle
    → Inner layer thin endothelium

Which blood vessel is this?

A

Artery

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14
Q
  • Small lumen
  • At tissue level
  • No valves
  • High pressure
  • No pulse
  • Thin wall
    → Outside basement membrane
    → Inside endothelial cells

Which blood vessel is this?

A

Capillary

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15
Q
  • Big Lumen (20µm-9mm)
  • Near surface of skin
  • Valves
  • Low pressure
  • No pulse
  • Thin wall
    → Outer layer CT
    → Minimal middle layer of smooth muscle
    → Inner layer thin endothelium

Which blood vessel is this?

A

Vein

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16
Q
  • Least permeable
  • Only exchange through diffusion → gas exchange

Which type of capillary is described here?

A

Continuous capillary

17
Q
  • Small openings
  • Covered by permeable membrane
  • Exchange through small channels → glucose, amino acids

Which type of capillary is described here?

A

Perforated/fenestrated capillary

18
Q
  • Gaps in basement membrane
  • Exchange of bigger molecules → fats, hormones, vitamins

Which type of capillary is described here?

A

Discontinuous capillary

19
Q

What are the 2 forms of water displacement in the human body?

A

hydrostatic and colloid-osmotic pressure

  • Passive exchange of water between capillary circulation and interstitial space
  • Exchange across a semipermeable membrane
20
Q

What are characteristics of hydrostatic pressure in the body?

A
  • High pressure in capillary, low pressure in tissue → Filtration from high to low pressure
  • Determined by blood pressure

→ Diffusion

21
Q

How does the colloid osmotic pressure work?

A
  • Has to do with concentration of particles in a solution
  • Blood contains large proteins like albumin or globulin → Can’t pass through capillary wall
  • Water moves to area with higher concentration of particles
  • Suction effect due to higher (e.g. protein) concentration
  • Evens out particle and water concentration on both sides of membrane
22
Q

How does water travel in colloid osmotic pressure?

A

from low particle concentration to high particle concentration

23
Q

Why does water despite the pressure systems accumulate in the body?

A

Net pressure release of hydrostatic pressure out of capillary > net pressure of colloid-osmotic pressure into capillary

More water is pushed into intersticial space than sucked back into the capillary

24
Q

How much water is moved into the interstitial space per day?

A

Approx. 8L

25
- Big lumen 15-75µm - On tissue level - Valves - Low pressure - Overlapping epithelial cells - No or discontinuous basement membrane - Peristaltic movement walls Which vessel is this?
Lymphatic capillary
26
- Small lumen 3-8µm - On tissue level - No valves - High pressure - Connected epithelial cells - Continuous or discontinuous basement membrane - Some constriction or dilation possible Which vessel is this?
Blood capillary
27
What are the main functions of the lymphatic system?
1. Tissue drainage 2. Return plasma proteins to circulation 3. Uptake of fats in bowel 4. Defence → production and distribution of lymphocytes
28
Which part of the body is drained by the right lymphatic duct which enters into the right subclavian vein?
Upper right torso Right arm Right side of neck and head
29
Which part of the body is drained by the thoracic duct which enters into the left subclavian vein?
Legs Lower torso Upper left torso Left arm Left side of neck and head
30
What are the biggest lymph vessels of the body?
thoracic duct (ductus thoracicus) and right lymphatic duct (lymphaticus dextra)
31
What is the biggest lymph node of the human body and where is it located?
Cisterna Chyli → one of the biggest lymph nodes Most inferior part of thoracic duct
32
What is the main function of lymph nodes?
- Filters out damaged cells, cancer cells, foreign particles - Release specialised blood cells (**t-lymphocytes**) → destroy damaged cells, cancer cells, foreign particles
33
What happens to lymph nodes when there is an infection ?
lymph node works harder and swells
34
The cavities of lymph nodes are filled with?
White blood cells / Leucocytes
35
What is the mechanism of intra-cellular oedema?
- Inadequate ATP production and functioning of sodium pump (Na+/K+ -ATPase) - Accumulation of Na+ in extracellular compartment - Leads to osmotic swelling of cells is the result → 2-3 times of normal size → May lead to cell death
36
Where can intra-cellular oedema often be observed?
In inflammatory tissues
37
What are the main reasons for extra-cellular oedema?
→ Increase in capillary blood pressure → Decrease in plasma colloid-osmotic pressure → Blockage of lymphatic drainage → Increase in capillary wall permeability
38
What happens if water is no longer constrained by hydrostatic and colloid osmotic pressure and the corresponding macromolecules?
Water reacts to forces of gravity and travels to the limbs (extra-cellular oedema)