Psychotherapy for adolescents and young adults at high risk for psychosis Flashcards
What is the aim of the study?
To conduct a PRISMA systematic review evaluating the efficacy of psychotherapeutic interventions in reducing the rates of conversion to psychosis in clinical high-risk individuals.
What methodology was used to identify relevant studies?
RCTs were identified in PubMed, Medline, and PsycINFO databases up to 30 November 2013.
How many studies met the review inclusion criteria?
Six studies comprising 800 participants.
What type of therapy was a core element in all six studies?
Cognitive behaviour therapy (CBT).
What was the conclusion of the study?
Cognitive behaviour therapy may be beneficial in delaying or preventing the onset of psychosis in clinical high-risk individuals, though effect sizes appear small.
What are some symptoms of the prodromal phase before psychosis onset?
Reduced ability to concentrate, decreased motivation, sleep disturbance, depression, anxiety, cognitive and social impairment, and decreased tolerance to normal stress.
What structured interviews are used for evaluating psychosis risk?
The Comprehensive Assessment of At-Risk Mental States (CAARMS) and the Structured Interview for Psychosis Risk Syndromes (SIPS).
What was a recent trial’s finding regarding omega-3 fatty acids?
A 12-week course of omega-3 fatty acids significantly reduced the likelihood of CHR participants developing psychosis compared to a placebo group.
What is a concern regarding pharmacological interventions in CHR individuals?
There is little evidence of lasting effects in preventing or delaying psychosis, and exposing individuals who may never develop psychosis to harmful side effects of antipsychotic medications.
Why is cognitive behaviour therapy (CBT) considered for CHR individuals?
CBT has demonstrated efficacy in acute and chronic psychosis, relapse prevention, and symptoms frequently comorbid in CHR populations such as depression and anxiety.
