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Pharm > Psychotherapeutics > Flashcards

Psychotherapeutics Flashcards

1
Q

Psychiatric disorder types

A

Organic

Function

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2
Q

Organic

A

Congenital or caused by injury

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3
Q

Functional

A

Partially of psychogenic origin

Psychosis, affective disorder, neurosis

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4
Q

Psychosis

A 
Disturbance of the functioning of ones personality with the loss of the perception of reality 
Most common schizophrenia 
Positive symptoms (agitation, delusions, auditory hallucinations)
Negative symptoms (flat affect, apathy)
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5
Q

Affective disorder

A 
Unipolar (involutional, reactive)
Or bipolar (alternating periods of depression and mania) also called manic depressive disorder
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6
Q

Necrosis

A

Less severe than psychosis
Anxiety, panic disorder, phobia, OCD
Emotional origin with physical symptoms

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7
Q

Antipsychotic agent groups

A 
Conventional agents (were used most often)
Atypical agents (used when resistance built to conventional agents)
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8
Q

Conventional antipsychotic agents

A

Low potency=more sedation, more autonomic side effects, more peripheral side effects

High potency=more extrapyramidal side effects, less sedation

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9
Q

Conventional antipsychotic agent pharmacological effects

A

Antipsychotic (calming emotions, suppress hallucinations and delusion)
Antiemetic (control nausea and vomiting)
Intractable hiccups
Drug withdrawal

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10
Q

Atypical antipsychotic agents pharmacological effects

A

Improved efficacy and fewer side effects

Effective against positive and negative symptoms

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11
Q

Atypical antipsychotic agents

A 
More nausea
Less anticholinergic side affects
Less sedation
Lower incidence of extrapyramidial 
No antiemetic effects
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12
Q

Atypical and conventional side effects

A 
Sedation
Extrapyramidal effects
Orthostatic hypotension
cV effects
Seizures
Anticholinergic effects
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13
Q

Extrapyramidal effects

A

Acute dystonia (muscle spasms)
Parkinsonism
Akathisia (compulsive motor activity)
Tardive dyskinesia (irreversible involuntary movements)

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14
Q

Tardive dyskinesia

A 
Women 40+
Large doses of phenothiazines
Gradual onset
Irreversible 
Movements coordinated and rhythmic
Effect exacerbated by drug withdrawal
Severe tmj pain
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15
Q

Anticholinergic effects

A

More often in conventional

Blurred vision, xerostomia

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16
Q

Antipsychotic drug interactions

A 
Cns depressant (additive, sedation, respiratory depression)
Epinephrine
Anticholinergic agents (additive, worsen dry mouth)
17
Q

Antidepressant agents use

A

Depression
Chronic pain adjuvant
Migraine

18
Q

Antidepressant agents

A 
Tricyclic
Second generation 
Selective serotonin reuptake inhibitors
Bupropion
Others
Monoamine oxidase inhibitors
19
Q

Tricyclic antidepressant

A

First generation
Differ in side effects
-in

20
Q

Tricyclic pharmacological effects

A

Feeling of well being, elevates mood
6 weeks to experience full effect
Sedation common (develops tolerance)

21
Q

Tricyclic adverse effects

A

Cns depressant
Anticholinergic
Increase heart rate, blood pressure, heart attack

22
Q

Tricyclic drug interactions

A

Amphetamines/Cns stimulants (increase heart rate and bp)
Maoi agent (fatal)
Anticholinergic (additive)

23
Q

Tricyclic uses

A

Depression
ODC
Anxiety

24
Q

Second generation

A

Fewer side effects
Fewer anticholinergic effects
Less cardio toxicity
Less sedative

25
Q

Selective serotonin reuptake inhibitors

A

Less side effect

Equal antidepressant effect to tricyclic

26
Q

Ssri adverse effects

A

Cns stimulation
Gi
Oral effects (dry mouth, taste changes, canker sores, glossitis)

27
Q

Bupropion

A

Dopamine-norepinephrine reuptake inhibitor

Also used for smoking cessation

28
Q

Bupropion adverse effects

A

Seizures
Gi
Cns

29
Q

Monoamine oxidase inhibitors

A

Inhibit mao enzyme
Drug interaction
Interaction with food (wine, aged cheese, fish) results in hypertensive crisis
Last choice drugs for depression

30
Q

Drug for bipolar depression

A

Mood stabilizers
Lithium
Valproate
Carbamazepine

31
Q

Epinephrine

A

Caution with tricyclic

Pharm (9 decks)

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