Psychostimulants and Cog Enhancers Flashcards
1
Q
Psychostimulants
- Schedule II due to High potential for Abuse / Diversion
- Monitor BP
- Watch for Weight Loss
- Insomnia
- Exacerbation of tics
- Decreased seizure threshold
A
Dextroamphetamine and Amphetamine
(Dexedrine, Adderall)
2
Q
Psychostimulants
- CNS stimulant, similar to amphetamine
- Schedule II
- Watch for Leukopenia or Anemia
- Monitor BP and CBC w/ differential
- Watch for Weight Loss, Insomnia, Exacerbation of Tics, Decreased seizure threshold
A
Methylphenidate (Ritalin, Concerta)
3
Q
Psychostimulants
- Inhibits presynaptic Norepinephrine reuptake –> Increased synaptic NorEpi and Dopamine
- Less appetitie Suppression and Insomnia
- Not classified as a Controlled substance
- Less Abuse Potential, Less Effective
- Rare Liver Toxicity
- Increased SI in Children / Adolescents
A
Atomoxetine (Strattera)
4
Q
Psychostimulants
- Used in Nacrolepsy, not ADHD
A
Modafinil (Provigil)
5
Q
Cognitive enhancers
- Reversible Acetylcholinesterase inhibitors
- Once-daily dosing
- Some GI side effects
- Mild to Moderate neurocognitive disorders (dementia)
A
Donepezil (Aricept)
6
Q
Cognitive enhancers
- Acetylcholinesterase inhibitors
- Twice-daily dosing
- GI side effects
- Mild to Moderate Neurocognitive disorders (dementia)
A
Galantamine (Razadyne)
7
Q
Cognitive enhancers
- Reversible Acetylcholinesterase inhibitors
- Twice-daily dosing
- Daily Patch form with fewer SE
- Mild to Moderate neurocognitive disorders (dementia)
A
Rivastigmine (Exelon)
8
Q
Cognitive enhancers
- NMDA (Glutamate) Receptor antagonist
- Moderate to Severe Neurocognitive disorder (dementia)
- Fewer SE than Cholinesterase inhibitors
- Should be used w/ Acetylcholinesterase inhibitor
A
Memantine (Namenda)
