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Psychiatry > Antipsychotics > Flashcards

Antipsychotics Flashcards

1
Q

Gen. Antipsychotics that block Dopamine (D2) receptors?

A

Typical 1st Generation Antipsychotics

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2
Q

Gen. Antipsychotics that block Dopamine (D2) and Serotonin (2A) receptors?

A

Atypical or 2nd Generation Antipsychotics

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3
Q

Antipsychotic

  • Typical
  • Low-potency
  • Commonly causes Orthostatic hypotension
  • Can cause Blue-gray skin discoloration
  • Photosensitivity
  • Rx for Nausea, Vomiting, and Intractable Hiccups
A

Chlorpromazine (Thorazine)

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4
Q

Antipsychotic

  • Typical
  • Low-potency
  • A/w Retinitis pigmentosa
A

Thioridazine (Mellaril)

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5
Q

Antipsychotic

  • Typical
  • Mid-potency
  • Higher risk of Seizures
  • Metabolite is an Anitdepressant
A

Loxapine (Loxitane)

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6
Q

Antipsychotic

  • Typical
  • Mid-potency
  • Can cause Ocular pigment changes
A

Thiothixene (Navane)

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7
Q
  • Antihistamine - results in sedation and weight gain
  • Anti-a1 adrenergic - results in Orthostatic Hypotension, Cardiac abnormalities, and Sexual dysfunction
  • Antimuscarinic - anticholinergic effects, resulting in dry mouth, tachy, urinary retention, blurry vision, constipation, and precipitation of narrow angle glaucoma
A

Anti-HAM effects

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8
Q

Antipsychotic

  • Atypical
  • Less likely to cause Tardive dyskinesia
  • Rx for refractory Schizophrenia
  • A/w Tachycardia adn Hypersalivation
  • Small risk of Myocarditis
  • Small risk of Agranulocytosis
  • Small risk of Seizures
  • Only antipsychotic shown to decrease the risk of suicide
A

Clozapine (Clozaril)

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9
Q

Antipsychotic

  • Atypical
  • Increased Prolactin
  • Orthostatic hypotension and Reflex tachycardia
  • Long acting injectable form
A

Risperidone (Risperdal)

Consta: Long acting injectable

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10
Q

Antipsychotic

  • Atypical
  • Less likely to cause Extrapyramidal side effects
  • SE:
    • Sedation
    • Orthostatic hypotension
A

Quetiapine (Seroquel)

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11
Q

Antipsychotic

  • Atypical
  • SE:
    • Weight gain
    • Sedation
A

Olanzapine (Zyprexa)

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12
Q

Antipsychotic

  • Atypical
  • Less likely to cause significant Weight gain
  • QTc prolongation
  • Must be taken with Food
A

Ziprasidone (Geodon)

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13
Q

Antipsychotic

  • Atypical
  • Unique mechanism of partial D2 agonism
  • Can be more activating (akathisia) and Less sedating
  • Less potential for Weight gain
A

Aripiprazole (Abilify)

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14
Q

Antipsychotic

  • Atypical
  • Must be taken w/ Food
  • Rx for Bipolar depression
A

Lurasidone (Latuda)

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15
Q

Atypical Antipsychotics Rx for Mania? (4)

A

Quetiapine (Seroquel)

Olanzapine (Zyprexa)

Aripiprazole (Abilify)

Risperidone (Risperdal)

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Psychiatry (12 decks)

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