Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Psych > Psychopharmacology > Flashcards

Psychopharmacology Flashcards

You may prefer our related Brainscape-certified flashcards:
Psychology 101 flashcards GRE® Psychology flashcards
1
Q

What dopamine pathway is associated with negative symptoms like social isolation and lack of hygiene?

A

Mesocortical

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What dopamine pathway is associated with positive symptoms like delusions?

A

Mesolimbic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What dopamine pathway is associated with extra pyramidal symptoms such as tardive dyskinesia?

A

Nigostriatal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What dopamine pathway is associated with galactorrhea and gynecomastia?

A

Tubule infundibular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What serotonin receptors are responsible for depressive symptoms?

A

5HT1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What serotonin receptors are responsible for decreased libido symptoms?

A

5HT2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What serotonin receptors are responsible for gastrointestinal symptoms?

A

5HT3/4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What populations of patients should not be on antipsychotics?

A

People with arrhythmias, people with epilepsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What effects do first generation antipsychotics have?

A

Anti adrenergic, antihistamine, anticholinergic (anti-muscarinic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the target if second gen atypicals?

A

D2 and 5hT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the potential side effects of clozapine?

A

Agranulocytosis, seizures, hypotension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the brand name, type and side effects of quetiapine?

A

Seraquil, second gen antipsychotic, can cause orthostasis and sedation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What class of drug, brand name, side effects to apiprazole?

A

Partial DA agonist (second generation) abilify,

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the restrictions for MAOI use?

A

Food restrictions (Tyramine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are potential side effects of TCA agents?

A

Fatal in overdoses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are potential uses of SNRIs?

A

comorbid pain syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is a major advantage of bupropion and what is its mechanism of action?

A

No associated sexual dysfunction - works by acting on NE and dopamine receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What are specific effects of mitazapine?

A

Promotes sleep and appetite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What are potential negatives side effects of lithium?

A

Tremor, weight gain, GI symptoms, Neurotoxicity, thyroid dysfunction, diabetes insipidus, T wave depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What are potential negative side effects of carbamazepine?

A

Steven Johnson rash, blood dyspraxia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What are potential negatives side effects of valproic acid?

A

Hepatitis, blood dyscrasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What benzos are liver sparing?

A

Ativan (lorezepam), oxazepam (serax), tamezepam (restoril)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What benzos pose a high risk for abuse? What benzos pose a low
Risk? Why?

A

Xanax - quick onset, short duration, high risk

Clonipin - long onset, long duration,
Low risk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What makes second generation antipsychotics different from first gen?

A

Second gen - lower incidence of extrspyramidal effects but higher incidence of metabolic syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

What are possible extrapyramidal symptoms that can result?

A

dystonia, parkinsonism, akathisia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

What schizophrenia medication is responsible for loss of night vision?

A

thioidazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

What are some common side effects of SSRIs?

A

sexual dysfunction, GI upset, headache, akathisia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

What antidepressent should be avoided in patients with an eating disorder?

A

wellbutrin (buproprion)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

What mood stabilizer and antipsychotic requires a pretreatment CBC to assess for agranulocytosis?

A

carbamazepine, clozapine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

What is a screening test that should be performed for individuals on seroquel?

A

slit eye lamp exam for cataracts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

What bipolar drug can cause birth defects?

A

valproate

32
Q

What is the treatment for a benzodiazepine overdose?

A

flumenzenil

33
Q

What are the symptoms of serotonin syndrome?

A

diarrhea, agitation, delirium, myoclonus, seizures

34
Q

What medication has been shown to reduce suicidality in schizophrenics?

A

clozapine

35
Q

What is the treatment for a MAO-I overdose?

A

low dose benzos

36
Q

What are the symptoms of serotonin syndrome?

A

diaphoresis, tachycardia, myoclonic jerks, hyperthermia

37
Q

Which benzodiazepines should be used in the treatment of alcohol withdrawal?

A

Lorazepam, oxazepam, tamezepam

38
Q

What is a therapeutic level of lithium? What does lithium toxicity look like?

A

0.5-1; tremor, nausea, diarrhea, ataxia

39
Q

How do you manage symptoms of akinesthia in a patient recently started on an antipsychotic?

A

prescribe beta blocker

40
Q

What is a common side effect thioridazine?

A

retinal pigmentation

41
Q

What tests should be performed when prescribing lithium?

A

electrolytes, thyroid studies, serum Cr BUN

42
Q

How do stimulants affect the tics of tourette’s?

A

exacerbate the tics

43
Q

What drug should never be prescribed with lithium (or at least be super careful)

A

NSAIDS, HCTZ (increase levels)

44
Q

What are some of the risks of SSRIs in pregnancy?

A

Persistent pulmonary hypertension

45
Q

What is a risk to the newborn of lithium?

A

Epstein anomaly

46
Q

What are the symptoms associated with SSRI discontinuation syndrome?

A

Dizziness, nausea, vomiting, fatigue and lethargy

47
Q

What common medications can interfere with lamotrigine?

A

OCPs

48
Q

What medication is most effective in the treatment of OCD?

A

Clomipramine

49
Q

What antidepressent reduces seizure threshold?

A

wellbutrin

50
Q

What are the risks associated with nefazaodone?

A

serious liver failure

51
Q

What are the major types of SNRIs on the market?

A

venlafaxine (effexor) and duloxetine (cymbalta)

52
Q

What kind of drug is trazodone?

A

serotonin receptor antagonist

53
Q

What are the uses of cymbalta (dulextine)

A

neuropathic pain and depression

54
Q

What are the side effects associated with lamictal?

A

SJS

55
Q

How do you treat extrapyramidal side effects?

A

benzotropine (anti-cholinergic), antihistaminergic (benadryl), amantadine

56
Q

What is the risk of TD if taking typical antipsychotic?

A

1% ever year

57
Q

What class of drug is mirtazepine and what is it used for?

A

alpha2 receptor antagonist - used for refractory depression and insomnia

58
Q

What class of drug is wellbutrin

A

norepinephrine/dopamine reuptake inhibitor

59
Q

What are the antimuscarinic side effects?

A

blurred vision, weight gain, urinary retention, tachycardia

60
Q

What class of medications is considered particularly effective in treating atypical depression?

A

MAOIs

61
Q

What meds frequently recommended for panic disorder?

A

SSRIs, TCAs

62
Q

What meds are frequently recommended for GAD?

A

SSRIs, venlafaxine

63
Q

What meds are frequently recommended for enuresis?

A

TCA (imipramine)

64
Q

What are the side effects associated with thorazine? What kind of med is it?

A

typical antipsychotic - low potency; orthostatic hypotension, nausea, vomiting, bluish skin discoloration

65
Q

What are examples of high potency typical antipsychotic?

A

haldol, fluphenazine (prolixin)

66
Q

How frequently does TD stay?

A

50% of cases spontaneously remit, 50% do not!

67
Q

How do you treat anticholinergic side effects?

A

benzotropine

68
Q

How do you treat extrapyramidal side effects?

A

benzotropine (anti-cholinergic), antihistaminergic (benadryl), amantadine

69
Q

What is the risk of TD if taking typical antipsychotic?

A

1% ever year

70
Q

What are some non -benzo hypotics and how do they work?

A

Zolpidem (ambien), eszopicone (Lunesta) – > selective benzo receptor binding

Benadryl

Rozerem (selective melatonin agonist)

Non benzy anxiolytics:

  • buspar - 5hT partial agonist
  • hydroxyzine = antihistamine
71
Q

What is the mechanism of action for Strattera?

A

presynaptic norepinephrine transporter inhibitor

72
Q

What medications do you need to worry about taking with OCPs?

A

lamotrigine

73
Q

What atypical antipsychotic truly reduces the risk of extrapyramidal symptoms?

A

clozapine

74
Q

What typical antipsychotic is especially concerning for patients that have a change in their EKG?

A

pimozide

75
Q

What medication is optimal for opioid detoxification?

A

buprenorphine - mixed opioid agonist/antagonist

76
Q

What medication is optimal for treatment of binge eating disorder and bulimia?

A

topiramate

Psych (17 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions