Mood Disorder Flashcards

1
Q

What are the SIGECAPS criteria for depression?

A

sleep, insomnia, guilt, energy, concentration, appetite, psychomotor, suicidiality

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2
Q

What are the criteria for dysthymia?

A

2 years of chronically depressed mood most of the time

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3
Q

What are the criteria for depression?

A

5 of criteria

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4
Q

What is the definition of bipolar I disorder?

A

one occurance of mania (only requirement), often periods of depression in between

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5
Q

What is the recommended treatment for bipolar disorder?

A

antipsychotics, benzos, mood stabilizer, ECT during manic episodes

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6
Q

What are the symptoms of mania?

A

distractibility, irritability, grandiosity, flight of ideas, activity, speech, thoughtlessness

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7
Q

What is a mixed episode?

A

criteria for both manic and major depressive episode met

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8
Q

What is the difference between mania and hypomania?

A

mania - lasts 7 days vs. hypomania 4 days

no major impairment in functioning, no psychotic features

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9
Q

What are the most common sleep problems associated with MDD?

A

difficulty falling asleep, early morning awakening

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10
Q

What is the etiology of MDD?

A

neurotransmitter deficiencies, high cortisol, abnormal thyroid axis, psychosocial events, genetics

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11
Q

What proporotion of patients show a response to antidepressants?

A

50-60%

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12
Q

What are the characteristics of an atypical depression?

A

hypersomnia, hyperphagia, reactive mood, reactivity to rejection

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13
Q

What is the definition of rapid cycling?

A

4 or more episodes in 1 year

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14
Q

What is the typical course of mania? How often do they reoccur?

A

3 months, 90% of time reoccur within 5 years

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15
Q

What are some of the prominent side effects of lithium?

A

weight gain, tremor, GI upset, polyruria

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16
Q

What are the major types of depression?

A

melancholy, atypical, catatonia, psychotic

17
Q

What is the definition of bipolar II disorder?

A

one or more depressive episodes with at least 1 hypomania

18
Q

What are the symptoms of dysthymic disorder? How do you distinguish it from depression?

A

critieria: concentration, hopelessness, appetite, insomnia, low energy, self esteem issues
depression for more than 2 years, 2 critiera, never asymptomatic for more than 2 months
NOTE: never have psychotic symptoms

19
Q

What is cyclothymic disorder?

A

alternating periods of hypomania with mild/moderate depressive symptoms

20
Q

What are the criteria for seasonal affective disorder?

A

2 consecutive years of major depressive episodes during same season

21
Q

What are the criteria for postpartum depression?

A

onset within 4 weeks

22
Q

What are the criteria for adjustment disorder?

A

symptoms within 3 months of event that impair functioning - symptoms resolve within 6 months

23
Q

What is the most effective treatment for depression with psychotic features?

24
Q

What percentage of concordance is there between monozygotic twins and depression?

25
How often does depression occur in stroke patients?
30-50% of the time
26
How frequently does postpartum depression occur?
10-15% of mothers
27
How long does the risk of post-stroke depression last?
up to 2 years
28
What is the lifetime risk of suicide in mood disorders?
10-15%
29
Women on antidepressants are at risk for...
depression
30
What is the strongest indication for ECt?
treatment resistant depression with recurrent suicidal ideation
31
What are the contraindications to ECT?
no heart attack in last 3 months, no increase in ICP (no mass lesion)
32
How many treatments of ECT may be necessary to have an effect in refractory depression?
10
33
What is the best medication prescription for someone with depression with psychotic features?
SSRI and antipsychotic
34
What is the best medication treatment for mania?
Valproate acid or lithium
35
What is the best medication to prescribe to an individual in mania acutely?
Antipsychotic and benzo
36
What percentage of people in major depression respond without therapy?
1/3
37
What are the criteria for bereavement?
Symptoms not too debilitating within 2 months of truama
38
What symptoms change first with antidepressent therapy?
Sleep symptoms
39
What part of the brain is responsible for serotonin release?
Raphe nuclei