Mood Disorder Flashcards

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1
Q

What are the SIGECAPS criteria for depression?

A

sleep, insomnia, guilt, energy, concentration, appetite, psychomotor, suicidiality

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2
Q

What are the criteria for dysthymia?

A

2 years of chronically depressed mood most of the time

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3
Q

What are the criteria for depression?

A

5 of criteria

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4
Q

What is the definition of bipolar I disorder?

A

one occurance of mania (only requirement), often periods of depression in between

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5
Q

What is the recommended treatment for bipolar disorder?

A

antipsychotics, benzos, mood stabilizer, ECT during manic episodes

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6
Q

What are the symptoms of mania?

A

distractibility, irritability, grandiosity, flight of ideas, activity, speech, thoughtlessness

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7
Q

What is a mixed episode?

A

criteria for both manic and major depressive episode met

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8
Q

What is the difference between mania and hypomania?

A

mania - lasts 7 days vs. hypomania 4 days

no major impairment in functioning, no psychotic features

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9
Q

What are the most common sleep problems associated with MDD?

A

difficulty falling asleep, early morning awakening

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10
Q

What is the etiology of MDD?

A

neurotransmitter deficiencies, high cortisol, abnormal thyroid axis, psychosocial events, genetics

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11
Q

What proporotion of patients show a response to antidepressants?

A

50-60%

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12
Q

What are the characteristics of an atypical depression?

A

hypersomnia, hyperphagia, reactive mood, reactivity to rejection

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13
Q

What is the definition of rapid cycling?

A

4 or more episodes in 1 year

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14
Q

What is the typical course of mania? How often do they reoccur?

A

3 months, 90% of time reoccur within 5 years

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15
Q

What are some of the prominent side effects of lithium?

A

weight gain, tremor, GI upset, polyruria

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16
Q

What are the major types of depression?

A

melancholy, atypical, catatonia, psychotic

17
Q

What is the definition of bipolar II disorder?

A

one or more depressive episodes with at least 1 hypomania

18
Q

What are the symptoms of dysthymic disorder? How do you distinguish it from depression?

A

critieria: concentration, hopelessness, appetite, insomnia, low energy, self esteem issues
depression for more than 2 years, 2 critiera, never asymptomatic for more than 2 months
NOTE: never have psychotic symptoms

19
Q

What is cyclothymic disorder?

A

alternating periods of hypomania with mild/moderate depressive symptoms

20
Q

What are the criteria for seasonal affective disorder?

A

2 consecutive years of major depressive episodes during same season

21
Q

What are the criteria for postpartum depression?

A

onset within 4 weeks

22
Q

What are the criteria for adjustment disorder?

A

symptoms within 3 months of event that impair functioning - symptoms resolve within 6 months

23
Q

What is the most effective treatment for depression with psychotic features?

A

ECT

24
Q

What percentage of concordance is there between monozygotic twins and depression?

A

70

25
Q

How often does depression occur in stroke patients?

A

30-50% of the time

26
Q

How frequently does postpartum depression occur?

A

10-15% of mothers

27
Q

How long does the risk of post-stroke depression last?

A

up to 2 years

28
Q

What is the lifetime risk of suicide in mood disorders?

A

10-15%

29
Q

Women on antidepressants are at risk for…

A

depression

30
Q

What is the strongest indication for ECt?

A

treatment resistant depression with recurrent suicidal ideation

31
Q

What are the contraindications to ECT?

A

no heart attack in last 3 months, no increase in ICP (no mass lesion)

32
Q

How many treatments of ECT may be necessary to have an effect in refractory depression?

A

10

33
Q

What is the best medication prescription for someone with depression with psychotic features?

A

SSRI and antipsychotic

34
Q

What is the best medication treatment for mania?

A

Valproate acid or lithium

35
Q

What is the best medication to prescribe to an individual in mania acutely?

A

Antipsychotic and benzo

36
Q

What percentage of people in major depression respond without therapy?

A

1/3

37
Q

What are the criteria for bereavement?

A

Symptoms not too debilitating within 2 months of truama

38
Q

What symptoms change first with antidepressent therapy?

A

Sleep symptoms

39
Q

What part of the brain is responsible for serotonin release?

A

Raphe nuclei