Cognitive disorders

Question 1

What is the definition of delirium?

Answer 1

Waxing and waning change in a patients

Consciousness, sun downing (daytime drowsiness)

Question 2

What are the causes of delirium?

Answer 2

Alcohol
Electrolyte abnormality
Intoxication
Oxygen hypoxia
Uremia

Trauma
Infection
Poisons
Seizures

Question 3

What medications should be absolutely avoided in individuals with delirium?

Answer 3

Benzos

Question 4

What are the DSM criteria for dementia?

Answer 4

Memory impairment
Cognitive disturbances (agnostic, apraxia, aphasia)

Question 5

What is the normal work up for reversible causes of dementia?

Answer 5

CBC, electrolytes, TFTs, VDRL, B12 and folate

Question 6

What score on the MMSE is considered dysfunctional?

Answer 6

Less than 25

Question 7

What are the major susceptibility genes for alz?

Answer 7

Apoe4

Question 8

What condition places individuals at greater risk for Alzheimer’s?

Answer 8

Down’s syndrome

Question 9

What medications are used to help manage Alzheimer’s?

Answer 9

Cholinesterase inhibitors (aricept, rivastigmine), NMDa antagonists

Question 10

What is the epidemiology of Alzheimer’s?

Answer 10

Women much more affected

Question 11

What are the symptoms associated with levy body dementia?

Answer 11

Waxing and waning. Hallucinations, sensitivity to neuroleptics

Question 12

What are the symptoms associated with Pick disease?

Answer 12

Personality changes, echolalia, poor insight

Question 13

What are the symptoms associated with HAD?

Answer 13

Decline in cognition, depression, apathy, social withdrawal

Question 14

How does Parkinson’s dementia respond to antipsychotic medications?

Answer 14

Exacerbated

Question 15

What are the symptoms associated wig CJD?

Answer 15

Myoclonus, stupor/coma/death, ataxia, cortical blindness