Psychiatry Flashcards
Drugs for ADHD?
- Methylphenidate
- Atomexatine
(and dexamfetamine)
SAME FOR YOUNG AND OLD
SSRIs
Citalopram
Fluoxetine
Sertraline
Paroxetine
Best SSRI for pt with chronic health problem
Sertraline
Less drug interactions
(and citalopram)
SSRI for < 18yrs?
Fluoxetine only
Careful monitoring to start
SNRIs?
Duloxetine
Venlafaxine
Diagnosis of ADHD?
Symptoms in at least 2 or more settings
At least moderate impairment on interviewing
DSM-IV criteria:
Inattentive symptoms - 6 or more
Hyperactivity-impulsivity symptoms - 6 or more
ICD-10 (Hyperkinetic disorder)
Inattentive symptoms - 6 or more
Hyperactivity - 3 or more
Impulsivity - 1 or more
First rank symptoms (Schneider)
Primary delusions Delusions of control Auditory hallucinations - 3rd person Somatic hallucinations Delusions of thought control - thought broadcasting - thought withdrawal - thought insertion
Weight gain most common in what antipsychotics?
Clozapine
Olanzapine
Phenothiazine
Typical antipsychotics MOA?
D2 antagonists
Typical antipsychotics examples?
Chlorpromazine
Prochlorperazine
Haloperidol
Flupentixol
Atypical antipsychotic examples?
Olanzapine Clozapine Risperidone Aripiprazole Quetiapine
Atypical antipsychotic MOA?
dopamine and 5HT2 antagonists
EPSE?
Extra-pyramidal side effects
More associated with TYPICALS rather than atypicals
Side effects of typical antipsychotics?
EPSE:
- tardive dyskinesia (invol. movements of mouth/tongue)
- Parkinsonism (cogwheel rigidity, bradykinesia etc)
- Akathisia (subjective motor restlessness)
- Acute dystonic reactions (oculogyric crisis and others)
Prolongued QT
Sedation
Hypotension
Neuroleptic malignant syndrome
Side effects of atypical antipyschotics?
Metabolic syndrome
Postural hypotension
Mild EPSE
Mild sedation
AGRANULOCYTOSIS especially clozapine