Infection & Immunity (inc antibiotics) Flashcards

1
Q

Cause hand-foot and mouth or herpangina

A

Coksackie A Virus

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2
Q

Antibiotics for meningococcal meningitis children in hospital?

A

Ceftriaxone if > 3 months

Cefotaxime + amoxicillin if < 3 months

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3
Q

Antibiotics for low severity CAP?

A

Amoxicillin (5 days)

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4
Q

Antibiotics for moderate-severity CAP?

A
  1. Consider 7-10 days

2. Dual therapy amoxicillin + macrolide

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5
Q

Antibiotics for high -severity CAP?

A

Dual antiobiotic therapy with beta-lactamase stable beta-lactam and macrolide.
eg co-amoxiclav + clarithromycin

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6
Q

Inital fluid resuscitation?

A

Crystalloid (Hartmanns, saline, etc)

500 ml bolus over 15 mins

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7
Q

Antibiotics for neutropenic sepsis?

A

Tazocin

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8
Q

Dose of adrenaline by age?

A

< 6 yrs = 150mg
6-12 yrs = 300mg
> 12 yrs = 500mg

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9
Q

Chronic bronchitis exacerbation abx?

A

Amoxicillin

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10
Q

Hospital-acquired pneumonia abx?

A

<5 days admission:
Co-amoxiclav/cefuroxime
>5 days admission
Piperacillin with tazobactam

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11
Q

Acute pyelonephritis abx?

A

Br-spec cephalosporin

or quinolone

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12
Q

Acute prostatitis abx?

A

Quinolone (cipro or ofloxacin)

Trimethoprim

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13
Q

Impetigo abx?

A

Top fusidic acid

Widespread = flucloxacillin or erythromycin

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14
Q

Cellulitis abx?

A

Flucloxacillin

Clarithromycin

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15
Q

Animal/human bite abx?

A

Co-amoxiclav

doxycycline + metronidazole

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16
Q

Mastitis abx (during breastfeeding)?

A

Flucloxacillin

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17
Q

Sinusitis abx?

A

Amoxicillin

Doxycycline

18
Q

Otitis media abx?

A

Amoxicillin

erythromycin

19
Q

Otitis externa abx?

A

If localized otitis externa, and serious enough = flucloxacillin

If diffuse acute otitis externa consider topical gentamicin + top steroid
Or acetic acid spray if mild

20
Q

Gonorrhoea abx?

A

Single dose of IM ceftriaxone + PO azithromycin

21
Q

Chlamydia abx?

A

Doxycycline
or
Azithromycin

22
Q

PID abx?

A

doxycycline + metronidazole
OR
ofloxacin + metronidazole

23
Q

Syphilis abx?

A

Benzathine benpen
OR
Doxycycline
or erythromycin

24
Q

Bacterial vaginosis abx?

A

Oral/top metronidazole
or
Top clindamycin

25
Q

Clostridium difficile abx?

A

Metronidazole

vancomycin if severe or 2nd episode

26
Q

Campylobacter abx?

A

Normally self limiting

Clarithromycin

27
Q

Salmonella abx?

A

Only treat invasive or severe infection

Ciprofloxacin

28
Q

Shigellosis abx?

A

Not indicated for mild cases

Ciprofloxacin

29
Q

Endocarditis initial blind therapy?

A

Amoxicillin

Consider adding low dose gentamicin

30
Q

Staphylococci native valve endocarditis abx?

A

Flucloxacillin

31
Q

Staphylococci prosthetic valve endocarditis abx?

A

Flucloxacillin + rifampicin + low dose gentamicin

32
Q

Endocarditis by fully senstitive strep abx?

A

Benzylpenicillin

33
Q

What are HACEK microorganisms?

A
Haemophilus
Actinobacillus
Cardiobacterium
Eikenella
Kingella
34
Q

Abx for HACEK endocarditis?

A

Amoxicillin + low dose gentamicin

35
Q

Typhoid fever abx?

A

Cefotaxime

36
Q

Peritonitis abx?

A

Cephalosporin + metronidazole

37
Q

Asymptomatic patients in contact with infectious syphilis abx?

A

Doxycycline

38
Q

Septic arthritis abx?

A

Flucloxacillin

39
Q

Purulent conjunctivitis abx?

A

Topical chloramphenicol

40
Q

Gingivitis abx?

A

Only if acute necrotising ulcerative

Metronidazole

41
Q

Giardiasis abx?

A

Metronidazole

42
Q

CURB-65?

A
Confusion
Urea (BUN > 19mg/dL)
Respiratory rate > 30
BP < 90/60
Age > 65
One point for each