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USMLE Step 1 Quick Notes > Psychiatry > Flashcards

Psychiatry Flashcards

1
Q

How does amitriptyline affect the heart?

A

QRS prolongation, QT prolongation, arrhythmias

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2
Q

What is a common first symptom of alcohol withdrawal?

A

Temulousness. Others are distress, agitation, anxiety, autonomic disturbance

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3
Q

What deals with involuntary responses?

A

Classical conditioning

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4
Q

What deals with voluntary responses?

A

Operant conditioning

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5
Q

What is identification (ego defense)?

A

Modeling behavior after another person who is more powerful (abused child after abuser)

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6
Q

What is repression?

A

Involuntary (vs suppression which is voluntary) withholding of idea or feeling

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7
Q

How long for Tourette’s?

A

> 1 year

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8
Q

What is the treatment for ADHD?

A

Methylphenidate, amphetamines, atomoxetine, clonidine

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9
Q

What is Rett disorder?

A

X-linked only in girls (males die in utero). Hand-wringing, retardation, ataxia

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10
Q

What is dissociative fugue?

A

Abrupt travel or wandering during period of dissociative amnesia.

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11
Q

How long for delusional disorder?

A

> 1 mo

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12
Q

Depersonalization vs dereleaziation?

A

Depersonalization: detachment from one’s body, thoughts, perceptions, actions
Derealization:
detachment from one’s neviornment

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13
Q

How long for manic episode?

A

Atleast 1 week

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14
Q

What is bipolar I?

A

Mania

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15
Q

What is bipolar II?

A

Hypomania and depression

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16
Q

How long for major depressive disorder?

A

Episodes 6-12 months with symptoms lasting >2 weeks

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17
Q

How do you tell bulimia and anorexia apart?

A

Anorexia their BMI is low but bulimia they are normal weight

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18
Q

How long for postpartum psychosis?

A

Days to 4-6 weeks

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19
Q

How long for pathologic grief?

A

6-12 mos; excessively intense can be > 6-12 mos

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20
Q

How long for GAD?

A

6 months at least

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21
Q

How long for PTSD?

22
Q

How long for acute stress disorder?

A

3 days - 1 month

23
Q

Diagnosis: mood reactivity, hypersomnia and weight gain, leaden paralysis, rejection sensitivty

A

Atypical depression

24
Q

What do lithium levels increase with?

A

ACE-I, NSAIDs, thiazides

25
Q

What is russell sign?

A

Dorsal hand calluses from induced vomiting (Russell sign)

26
Q

What is a sensitive indicator of alcohol use?

27
Q

Diagnosis: pupillary dilation, hallucinations, paranoid ideations, sudden cardiac death?

A

Cocaine intoxication

28
Q

What is venlafaxine used for?

A

Panic disorder and anxiety

29
Q

What is varenicline?

A

Used for nicotine withdrawal. It is a nicotine AchR partial agonist. Reduces withdrawal cravings and reward of nicotine.

30
Q

What drug intoxication of withdrawal: perceptual distortion, depersonalization, flashbacks, psychosis, paranoida?

31
Q

What do use to treat OCD?

A

SSRI or clomipramine

32
Q

What are the high potency antipsychotics?

A

Fluphenazine, Trifluoperazinem, Haloperidol

33
Q

What are the low potency antipsychotics?

A

Thioridazine, Chlorpromazine

34
Q

What do you treat EPS side effects of antipsychotics with?

A

Benztropine or diphenhydramine

35
Q

Corneal deposits with what med?

A

Chlopromazine

36
Q

Retinal deposits with what med?

A

Thioridazine

37
Q

How does lithium work?

A

Possibly through inhibition of PIP3 cascade

38
Q

How long does buspirone take to effect?

39
Q

MC toxicity for SNRI?

40
Q

Major toxicity with TCA?

A

Convulsions, coma, cardiotoxicity (arrhythmias since they inhibit Na channels)

41
Q

Which TCA is less sedating but has higher seziures threshold?

A

Despiramine

42
Q

How does Mirtazapine work?

A

a2 autoreceptor antagonist and POTENT serotonin receptor antagonist

43
Q

How does Trazodone work?

A

Serotonin and alpha 1 adrenergic antagonist

44
Q

Why is methadone good for opioid addiction?

A

It has a long half life

45
Q

What is benztropine?

A

Antimuscarinic used for parkinson’s.

46
Q

What are the two drugs that inhibit peripheral dopamine degradation?

A

Carbidopa: LAAD inhibitor
Entacapone: COMT inhibitor

47
Q

Why do people get tardive dyskinesia on antipsychotics?

A

Long term use causes hypersensitivity or upregulation of dopamine receptors and concomitant decrease in cholinergic tone in the striatum

48
Q

What would confusion, sleepiness and dementia in an acute setting for an old person be?

A

Delirium (from meds, infections etc)

49
Q

What age for conduct disorder?

50
Q

How long for adjustment disorder?

USMLE Step 1 Quick Notes (17 decks)

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