Psychiatry

Question 1

How does amitriptyline affect the heart?

Answer 1

QRS prolongation, QT prolongation, arrhythmias

Question 2

What is a common first symptom of alcohol withdrawal?

Answer 2

Temulousness. Others are distress, agitation, anxiety, autonomic disturbance

Question 3

What deals with involuntary responses?

Answer 3

Classical conditioning

Question 4

What deals with voluntary responses?

Answer 4

Operant conditioning

Question 5

What is identification (ego defense)?

Answer 5

Modeling behavior after another person who is more powerful (abused child after abuser)

Question 6

What is repression?

Answer 6

Involuntary (vs suppression which is voluntary) withholding of idea or feeling

Question 7

How long for Tourette’s?

Answer 7

> 1 year

Question 8

What is the treatment for ADHD?

Answer 8

Methylphenidate, amphetamines, atomoxetine, clonidine

Question 9

What is Rett disorder?

Answer 9

X-linked only in girls (males die in utero). Hand-wringing, retardation, ataxia

Question 10

What is dissociative fugue?

Answer 10

Abrupt travel or wandering during period of dissociative amnesia.

Question 11

How long for delusional disorder?

Answer 11

> 1 mo

Question 12

Depersonalization vs dereleaziation?

Answer 12

Depersonalization: detachment from one’s body, thoughts, perceptions, actions
Derealization:
detachment from one’s neviornment

Question 13

How long for manic episode?

Answer 13

Atleast 1 week

Question 14

What is bipolar I?

Answer 14

Mania

Question 15

What is bipolar II?

Answer 15

Hypomania and depression

Question 16

How long for major depressive disorder?

Answer 16

Episodes 6-12 months with symptoms lasting >2 weeks

Question 17

How do you tell bulimia and anorexia apart?

Answer 17

Anorexia their BMI is low but bulimia they are normal weight

Question 18

How long for postpartum psychosis?

Answer 18

Days to 4-6 weeks

Question 19

How long for pathologic grief?

Answer 19

6-12 mos; excessively intense can be > 6-12 mos

Question 20

How long for GAD?

Answer 20

6 months at least

Question 21

How long for PTSD?

Answer 21

> 1 month

Question 22

How long for acute stress disorder?

Answer 22

3 days - 1 month

Question 23

Diagnosis: mood reactivity, hypersomnia and weight gain, leaden paralysis, rejection sensitivty

Answer 23

Atypical depression

Question 24

What do lithium levels increase with?

Answer 24

ACE-I, NSAIDs, thiazides

Question 25

What is russell sign?

Answer 25

Dorsal hand calluses from induced vomiting (Russell sign)

Question 26

What is a sensitive indicator of alcohol use?

Answer 26

GGT

Question 27

Diagnosis: pupillary dilation, hallucinations, paranoid ideations, sudden cardiac death?

Answer 27

Cocaine intoxication

Question 28

What is venlafaxine used for?

Answer 28

Panic disorder and anxiety

Question 29

What is varenicline?

Answer 29

Used for nicotine withdrawal. It is a nicotine AchR partial agonist. Reduces withdrawal cravings and reward of nicotine.

Question 30

What drug intoxication of withdrawal: perceptual distortion, depersonalization, flashbacks, psychosis, paranoida?

Answer 30

LSD

Question 31

What do use to treat OCD?

Answer 31

SSRI or clomipramine

Question 32

What are the high potency antipsychotics?

Answer 32

Fluphenazine, Trifluoperazinem, Haloperidol

Question 33

What are the low potency antipsychotics?

Answer 33

Thioridazine, Chlorpromazine

Question 34

What do you treat EPS side effects of antipsychotics with?

Answer 34

Benztropine or diphenhydramine

Question 35

Corneal deposits with what med?

Answer 35

Chlopromazine

Question 36

Retinal deposits with what med?

Answer 36

Thioridazine

Question 37

How does lithium work?

Answer 37

Possibly through inhibition of PIP3 cascade

Question 38

How long does buspirone take to effect?

Answer 38

1-2 weeks

Question 39

MC toxicity for SNRI?

Answer 39

Inc BP

Question 40

Major toxicity with TCA?

Answer 40

Convulsions, coma, cardiotoxicity (arrhythmias since they inhibit Na channels)

Question 41

Which TCA is less sedating but has higher seziures threshold?

Answer 41

Despiramine

Question 42

How does Mirtazapine work?

Answer 42

a2 autoreceptor antagonist and POTENT serotonin receptor antagonist

Question 43

How does Trazodone work?

Answer 43

Serotonin and alpha 1 adrenergic antagonist

Question 44

Why is methadone good for opioid addiction?

Answer 44

It has a long half life

Question 45

What is benztropine?

Answer 45

Antimuscarinic used for parkinson's.

Question 46

What are the two drugs that inhibit peripheral dopamine degradation?

Answer 46

Carbidopa: LAAD inhibitor Entacapone: COMT inhibitor

Question 47

Why do people get tardive dyskinesia on antipsychotics?

Answer 47

Long term use causes hypersensitivity or upregulation of dopamine receptors and concomitant decrease in cholinergic tone in the striatum

Question 48

What would confusion, sleepiness and dementia in an acute setting for an old person be?

Answer 48

Delirium (from meds, infections etc)

Question 49

What age for conduct disorder?

Question 50

How long for adjustment disorder?