Behavioral Science Flashcards
What is phase I?
Is it safe?
What is phase II?
Does it work?
What is phase III?
Is it good or better?
What is phase IV?
Can it stay?
What is incidence?
of new cases/ population at risk
What is prevalence?
of existing cases/population at risk
What is Relative risk reduction?
1-RR
What is precision?
Same as reliability
What is accuracy?
Same validity. Measured against a gold standard
What are the three major selection biases?
Berkinson: looking only at inpatients
Loss to follow up
Healthy worker and voluntary bias: study pop healthier than general population
What is hawthorne effect?
Example of measurement bias. Groups behave differently because they know they’re being studied
What is procedure bias?
Subjects in different groups not treated the same
What are cross over studies for?
To reduce confounding bias
How to reduce lead time bias?
Measure back end survival: adjust survival according to severity of disease time of diagnosis
What is alpha?
Type I error
What is beta?
Type II error
How is power increased?
Increased sample size, expected effect size, precision of measurement
What increases statistical power?
Meta analysis
How many months of life expectancy must you have for hospice care?
What is a cross sectional study?
Measuring exposure and outcome simultaneously (“snapshot”)
What should be considered when evaluating a screening test?
Lead time bias (time for diagnosis to death seems longer because it was diagnosed earlier than normally would’ve)
What is attrition bias?
Form of selection bias: loss to follow up
What is effect modification?
Stratifying the data will show a significant difference?
What is a confounder (vs effect modification)?
Stratifying the data will not show significant difference