Psychiatry Flashcards

1
Q

General anxiety disorder dx, tx

A

6+ months
3+ somatic signs
Worry about multiple entities
Causes dysfunction

Benzos ==> eventually taper

  1. SSRI’s
  2. Buspirone
  3. SNRI
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2
Q

Benzo overdose tx w/ mechanism

A

Flumazenil

Competitive GABA antagonist

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3
Q

Obsessive compulsive disorder dx, tx*

A

Obsessions: persistent, unwanted ideas
Compulsions: repeated acts to relieve anxiety
Ego-dystonic (aware of absurdity)

  1. SSRI
  2. CBT
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4
Q

Panic disorder dx, associations, tx

A

Discrete moment of fear
4+ signs: tachypnea, palpitations, sweating, chest pain, nausea, fear of dying, depersonalization
1+ month of fear over recurrence causing behavior change
*Must screen for agoraphobia

*Depression, bipolar, substance abuse

  • Acute: Benzo (taper if needed)
    1. SSRI
    1. CBT
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5
Q

Phobia disorders dx, tx*

A

Excessive fear leading to dysfunctional avoidance
Ego-dystonic

*1. CBT ==> first-line for SINGLE phobia like flying!
*2. Beta blocker or benzo if situational
Rarely SSRI

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6
Q

Post-traumatic stress disorder dx, subtype*, tx

A

s/p threatening event
Avoidance, hypervigilance, numbed responsiveness
sx for 1+ month

*Acute-stress disorder: PTSD lasting < 1 month

Short term:
Beta-blockers
Alpha-agonists

Long-term:
SSRI
Support groups

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7
Q

Dementia dx, tx

A
Memory impairment plus 1+ sx:
[4A's]
Amnesia
Aphasia (language impairment)
Apraxia (motor impairment)
Agnosia (recognition impairment)
Executive dysfunction
Personality change
STABLE CONSCIOUSNESS (unlike delirium)

Cholinesterase inhibitors
Antipsychotics
Environmental cues
AVOID benzodiazepines!

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8
Q

Delirium dx, tx

A

Waxing/waning consciousness (unlike dementia)
Altered cognition
Perceptual disturbances
Worsening at night
2/2 underlying medical cause!!! ==> find it!

Environmental cues
Antipsychotics

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9
Q

Major depressive disorder dx, subtypes*, tx** including refractory cases

A
2+ weeks
Depressed mood or anhedonia and...
4+ SIGECAPS 
Sleep change
Interest loss
Guilt/worthlessness
Energy loss
Concentration loss
Appetite increase/decrease
Psychomotor agitation/retardation
Suicidality

Psychotic
Post-partum (within 1 month)
Seasonal
*Dysthymia: milder but 2+ years
Bereavement: gradually waning with time, generally less severe, less self-loathing
*Persistent complex bereavement: 1+ year of depression with symptoms ALL focused on deceased
Adjustment disorder: 2/2 event, doesn’t meet MDD criteria, impairs functioning, lasts >1 month but > 6 months ==> psychotherapy instead of SSRI

  1. SSRI ==> expect 4-6 weeks for change; continue minimum 6 months if effective without severe side effects ==> switch class after 2 refractory attempts*
  2. ECT if refractory
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10
Q

ECT s/e*

A

*Anterograde amnesia

Headache, nausea, skin burns

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11
Q

Bipolar disorder dx, relevant features, subtypes, tx

A
1+ week of elevated, irritable mood plus 3+ DIGFAST mania criteria: 
Distractibility
Irresponsibility
Grandiosity
Flight of ideas
Agitation (psychomotor)
Sleep decrease
Talkative (pressured speech)
SSRI's may trigger
Psychotic episodes common
Suicide risk! 
Rule out substance abuse
10% risk if parent or sibling has it*

1: manic episode
2: depressive episode + hypomanic episode
Rapid cycling: 4+ episodes of any in one year
Cyclothymic: alternating episodes for 2+ years

*Acute mania:
antipsychotics [haloperidol] & hospitalize
*Long-term:
Mild bipolar: mood stabilizer or atypical antipsychotic mono therapy
Severe bipolar: mood stabilizer [lithium] + antipsychotic
Bipolar II:
Mood stabilizer first, then possibly antidepressant (afterward to prevent inducing mania)

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12
Q

Antipsychotics mechanism, names, side-effects*

A

Typicals: BLOCK D-2 receptor
Haloperidol, fluphenazine, chlorpromazine
Extrapyramidal (see flashcard)
Anticholinergic (dry mouth, urinary retention, constipation)
NMS (fever, rigidity, CK elevation) ==> dantrolene or bromocriptine
Prolacinemia 2/2 dopamine blockade*
Seizures
QT prolongation

Atypicals: D-2* and serotonin receptor blockage
Ziprazidone, quetipine, risperidone, olanzipine, aripiprazole, clozapine, fluphenazine (depot…for non-compliant)
Prolactinemia 2/2 dopamine blockade*
Weight gain* (especially olanzipine and clozapine ==> monitor glucose and lipids)
QT prolongation
Risperidone: most likely to cause extrapyramidal sx
**Clozapine only: tardive dyskinesia, agranulocytosis
(weekly CBC)

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13
Q

Antidepressant names, s/e*, contraindications

A

SSRIs-
Fluoxetine, citalopram etc.
Sexual, GI etc.
MAO-i ==> serotonin syndrome; pregnancy

Atypicals-
*Bupropion: seizures ==> contraindicated in epileptics and anorexia
Mirtazipine: sedation
Trazodone: sedation, priapism

SNRIs-
Venlafaxine, duloxetine
Hypertension

TCAs-
Nortriptyline, amitryptiline, desipramine
“Tri-C”: seizure, coma, dry mouth, dilated pupils, widened QRS ==> reverse with sodium bicarb**

MAO-i-
Selegiline, tranylcypromine, isocarboxazid
Hypertensive* crisis 2/2 tyramines (wine, cheese)
SSRI’s ==> serotonin syndrome

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14
Q

Mood stabilizer names, s/e, contrandications

A

Lithium
DI, hypothyroid* (test thyroid function before initiating)
Fetal: ASD & Ebstein’s tricuspid anomaly
Toxicity > 1.5 ==> ataxia, renal failure
(always see Cr if stem gives CBC
)

Carbamazepine
SJS, aplastic anemia

Valproic acid
Agranulocytosis, pancreatitis, hepatotoxicity

Lamotrigine
SJS

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15
Q

Post-partum disorder ddx

A

“Blues”:
Within 2 weeks
Sadness
No harm thoughts

Psychosis: 
2-3 weeks post-delivery
Depression
Delusions
Possible harm thoughts

Depression:
1-3 months post-delivery
Psychosis
+ harm thoughts

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16
Q

Personality disorders general characteristics, clusters with subtypes*, tx

A
"MEDIC" 
Maladaptive
Enduring
Deviant
Inflexible
Causing social impairment

“Weird, Wild, Worried Wimp”

CLUSTER A
Paranoid
Schizoid: isolated loners
Schizotypal: magical thinking, ideas of reference (seeing reference in everyday media
)

CLUSTER B
Borderline: unstable relationships, self-harm history, manipulative, splitting*
Histrionic: excessively emotional, sexual
Narcissistic: entitled, lacking empathy
Antisocial: violates others without remorse; conduct disorder as child

CLUSTER C*
OCD:  perfectionist, ego-syntonic
Avoidant*:  fear of rejection, inadequacy, isolation DESPITE desire for friendship (unlike schizoid*)
Dependent*:  submissive, clingy
----
Psychotherapy
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17
Q

Schizophrenia age, dx*, subtypes** with prognosis, ddx, tx

A

Males: 18-25
Females: up to 35

*6+ months
2+ of following:
Positive symptoms: hallucinations, delusions (fixed, false belief), disorganized speech, bizarre behavior ==> more treatment sensitive
Negative symptoms: flat affect, poverty of speech, anhedonia

Paranoid: delusions, hallucinations, intact cognition ==> best prognosis
Disorganized: flat affect, disordered speech and behavior ==> worst prognosis
Catatonic: motor defects, echolalia, echopraxia, mutism

  • Brief pyschotic < 1 month
  • Schizophreniform < 6 months
  • Schizoaffective = schizophrenia plus mood disorder features (i.e. mania, depression*)

Antipsychotics: atypicals are first line due to fewer side effects

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18
Q

Extrapyramidal side-effect symptoms, tx

A

DYSTONIA
Immediate onset tonic muscle contraction
Anticholinergics: benztropine*, diphenhydramine

DYSKINESIA
Days-later onset of pseudoparkinsonism (bradykinesia, masked facies, tremor)
Anticholinergic: benztropine*
Dopaminergic: amantadine

AKATHISIA
Weeks-later restlessness
Beta blockers or anticholinergic

TARDIVE DYSKINESIA*
Months-later stereotypical hyperkinetic oral-facial movement 2/2 dopamine blockade
Anticholinergics or decreasing dose may worsen
Often irreversible

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19
Q

ADHD dx, tx

A

6+ months
2+ settings
6+ symptoms of inattention and/or hyperactivity

Methylphenidate (ritalin)
Amphetamines
Antidepressants

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20
Q

Rett disorder presentation

A

Females only

Progressive impairment after 5 months of normal development

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21
Q

Childhood disintegrative disorder presentation

A

Regression after 2 years of normal development

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22
Q

Conduct disorder dx

A

1+ year
Violating rights of others
Progresses to antisocial disorder

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23
Q

Oppositional defiant dx

A

6+ months
Negative, defiant behavior towards authority
May progress to conduct disorder

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24
Q

Retardation IQ scores

A

Mild: 50-70
Moderate: 35-50
Severe: 20-34
Profound: <20

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25
Q

Tourette’s dx, associations, tx

A

< 18 y/o
1+ year
Motor tics
Vocal tics (coprolalia = obscene word repetition)

ADHD
OCD*

Antipsychotic*

26
Q

Substance abuse dx

A
1+ year of 1 or more: 
Failure to fulfill responsibilities 
Use in hazardous situations
Legal problems
Recurrent use despite social problems
27
Q

Substance dependence dx

A
1+ year of 3+ of following: 
Tolerance (more to obtain desired effect)
Withdrawal sx
Failed attempts to cut down
Significant time spent obtaining
Isolation
Consumption of greater amounts than intended
Continued use despite problems 2/2 drug
28
Q

Alcoholism dx, withdrawal signs*, tx hospital and long-term

A
2+ "CAGE"
Cutting back need
Annoyed when criticized
Guilty 
Eye opener

6 hrs: anxiety, palpitations ==> 1-2 days: seizures, hallucinations ==> 2-4 days: DT’s fever, hypertension, tachycardia, hallucinations

HOSPITAL
Benzo taper
Multivitamins w/ folic acid
Thiamine before glucose (glucose depletes thiamine, thus prevents Wernicke’s)

LONG-TERM
Disulfiram or naltrexone

29
Q

Signs of substance abuse* and withdrawal* with reversal agents

A

OPIOIDS
Pupil constriction, respiratory depression
Dilated pupils, pain, sweating, GI upset* ==> no seizures & not life-threatening
Naloxone or naltrexone

AMPHETAMINES
Pupil dilation, agitation, seizures
Anxiety, lethargy
Haloperidol

COCAINE
Pupil dilation, cardiac ischemia, agitation
Lethargy, anxiety
Haloperidol

PHENCYCLIDINE (PCP)*
Combativeness*, vertical/horizontal/rolling nystagmus
None
Benzo or haloperidol

LSD*
Anxiety, delusion, hallucination, pupil dilation
Less aggression and more pronounced hallucinations than PCP*

30
Q

Anorexia vs bulimia dx, complications**, pill to avoid, when to hospitalize*

A

< 85% expected body weight
Ego-syntonic (delusion as fat)
Dental erosions, enlarged parotids, dorsal scars
Bradycardia, hypotension, lanugo (fine, soft hair)
Subtypes: restrictive or binge & purge

Osteoporosis*
Elevated cholesterol
Amenorrhea
Mitral valve prolapse
Stress fractures
Arrhythmia
Mortality > 10% 2/2 suicide or medical complications
**Small for gestational age...even if only formerly anorexic! 

Normal - overweight
3+ months of 2x/week of binging ==> purge/fasting
Ego-dystonic (aware of problem)
Dental enamel erosions, enlarged parotids, dorsal scars

Lower mortality
More easily treatable
Similar complications
—-

Bupropion decreases seizure threshold
----
Hypokalemia
Bradycardia
BMI < 18
31
Q

Sexual interest change with age:

A

None

32
Q

Primary insomnia dx, tx

A

1+ month
3x / week
Unrestful sleep
NOT caused by medical or psychiatric condition

  1. good sleep hygiene (limit caffeine, sleep schedule, am exercise, nighttime bath etc)
  2. <2 week of sleep aids: diphenhydramine, zoldipem, trazadone
33
Q

Narcolepsy dx, features, tx

A

> 3 months
Decreased REM
Sleep attacks

Cataplexy loss of muscle tone
Hypnogogic/pompic hallucination
Sleep paralysis

Scheduled naps
Stimulants

34
Q

Sleep apnea types, tx

A

Central: both airflow and respiratory effort cease
Peripheral: obstruction 2/2 obesity, tongue, etc

Central: bipap
Peripheral: cpap

35
Q

Somatoform disorder definition, types, tx

A

Unconscious production of sx

  1. Somatization
    Female&raquo_space;> male
    Chronic complaints of multiple organs: GI, neurologic, pain, sexual
    Frequent physician visits*

1.5 Somatic symptom disorder (maybe different than above?)
1+ somatic complaints, including pain
>6 months
Causing severe impairment

  1. Conversion
    Usually 2/2 stressful event
    Implausible severe sensory/motor dysfunction (blind, seizure, paralysis)…often indifferent to them “la belle indiference”
    Self-resolving
  2. Hypochdriac/”illness anxiety disorder”
    Male = female
    Debilitating concern despite NO REAL SYMPTOMS* and REASSURANCE
    Frequent apt
  3. Body dysmorphic
    Female slightly more
    Debilitating self image concern
    SSRI may help; repeat appointments; reassurance doesn’t help*
36
Q

Fictitious disorder definition, types*

A

Cognizant fabrication of sx

  1. Munchausen*: for primary gain of sick role; often health workers
  2. Munchausen by proxy: fabricating sx in another person also for primary gain
  3. Malingering*: fabrication for secondary gain (pain seeking, $$)
37
Q

Abuse signs, sequelae, tx

A

Late-presentation of illness
Frequent ER visits
Shifty behavior or partner

PTSD
Suicide attempt

Document everything!!

38
Q

Suicide risks, dx, tx

A
SAD PERSONS
Sex (males complete; females attempt more)
Age (>45!!!)
Depression / mental disorder
Previous attempt
Ethanol/substance 
Rational thought 
Sickness (chronic)
Organized plan / access
No spouse
Social support dirth

Ask DIRECTLY

If endorsing ==> immediate hospitalization (even against will)
SSRI increase risk early by increasing energy…observe

39
Q

Trichtillomania dx, tx

A

Pulling hair to relieve anxiety

No underlying derm condition

40
Q

Delusional disorder dx*

A

1+ month
1+ delusion
No other psychotic symptoms
Otherwise well-functioning

41
Q

Normal ages for imaginary friends*

A

2-6

42
Q

Folie a deux dx, tx

A

One person’s delusion becomes shared by another close relation

Interview separately

43
Q

Defense mechanisms

A

Do them once finished

44
Q

Defiant teenager workup*

A

Interview together and separately with parents

*Toxicology screen

45
Q

HIPAA stuff to know*

A

Information may be released by verbal or written consent

Information may be released over the phone without proof of identity

46
Q

Neuroimaging findings in psychiatric disorders*

A
Autism:  increased total volume
Schizophrenia:  enlarged ventricles
PTSD:  smaller hippocampus
Panic disorder:  smaller amygdala
OCD:  orbitofrontal cortex changes
47
Q

Kleptomania dx, tx

A

Anxiety-induced urge to steal
Often small value
Regret post-stealing

*CBT

48
Q

Best option for patients refusing treatment*

A

Ask why!!

49
Q

Hospice referral criteria*

A

<6 month prognosis

50
Q

Vaginismus/pelvic pain/penetration disorder dx*

A

6+ months
Pain or tenseness with penetration
Causing significant impairment

51
Q

Buproprion indications, s/e

A

Atypical antidepressant
Smoking cessation aid
==> if patient is depressed and wants to quit, this may be best option*

Decreases seizure threshold!
Contraindicated with MAO-i

52
Q

When its okay to proceed with emergency procedure without consent*

A

No living will or advanced directives
Patient is not able to provide consent
*Even if Jehova’s witness, according to family

53
Q

Dissociative fugue vs dissociative amnesia*

A

Fugue: TRAVEL, amnesia, unable to identify self
Amnesia: forgetting important life events usually 2/2 stressor

54
Q

When minors can receive confidential, parental consent-free care*

A

STD
Pregnancy
Mental illness
Emancipated minor 13+: armed services, marriage, a parent*, living alone or financial independence

55
Q

Pediatric sexual abuse signs*

A

TRIAD:
Sudden behavioral change
Unstable economic background
Parent with substance abuse

56
Q

Breaking bad news approach*

A

SPIKES
Setting up: privacy, ask if family are desired
Perception: assess understanding of medical situation
Invitation: how much they want to know
Knowledge: warn of bad news and drop the bomb
Empathy
Strategy

57
Q

Reporting HIV or other STD to cuckolded partner*

A

Encourage partner to do it… but explain that health department will notify the partner if not

58
Q

When to discontinue lithium in bipolar patients*

A

1 episode: after 2 stable years

2 episodes: many years, if not lifetime

59
Q

Circumstantiality vs. tangentiality*

A

Circumstantial: eventually returns to topic
Tangential: deviates totally

60
Q

Mother vs fetus ethics*

A

Mother has autonomy over fetus as long as she has capacity