Psychiatric Drugs Flashcards
Diazepam trade name?
Valium
Valium classification?
Benzodiazepine
Valium actions?
Crosses the blood-brain barrier in the cerebral motor cortex to suppress seizure activity and cause CNS slowing. It will stop active seizure, but it does not prevent them. Does not have any analgesic properties.
Valium onset/duration?
IV: 1-5 min
IM: 15-30 min
IV/IM: 15-60 min
Valium indications?
acute anxiety, alcohol withdrawal, cocaine overdose, seizures, status epilepticus, sedation prior to cardioversion or transcutaneous pacing
Valium contraindications?
CNS depressant, hypotension, respiratory depression, hypersensitivity, alcohol intoxication
Valium side effects?
Respiratory depression, hypertension, confusion, nausea, vomiting, drowsiness, blurred vision
Valium route of administration?
IVP (slow)
Valium adult dose for seizures?
5mg over 2 min IV every 5-10 min as needed
(max dose of 30mg) or 10mg IM
Valium adult dose for cardioversion or transcutaneous pacing?
5-15mg IV, 5-10 min before procedure
Valium peds dose for 30 days-5 years old?
0.2-0.5mg slow IV every 2-5 min
max dose of 5 mg
Valium peds dose for >5 years old?
1mg IV every 2-5 min
max dose of 10mg
Valium supply?
5mg/mL or 10mg/2mL vials
Valium special considerations?
Reduce dose by 50% in geriatric population.
Flumazenil (Romazicon) is the anti-dose
Haloperidol trade name?
Haldol
Haldol classification?
Antipsychotic
Haldol actions?
Blocks the dopamine receptors in the brain that are responsible for mood and behavior
Haldol onset/duration?
IM: 30-60 min / 12-24 hours
Haldol indications?
Acute psychotic episodes, sedation of agitated patient
Haldol contraindications?
CNS depression, coma, hypersensitivity, pregnancy, Parkinson’s disease
Haldol side effects ?
Dystonia, hypotension, orthostatic hypotension, nausea, vomiting
What to administer for dystonia?
25-50mg of Benadryl
Haldol route of administration?
IV, IM
Haldol adult dose?
5mg IV, injected over 30 seconds
10mg IM
Haldol supply?
5mg/mL
Ketamine trade name?
Ketalar
Ketamine classification?
Nonbarbituate anesthetic
Ketamine actions?
Acts on the limbic system and cortex to block afferent transmissions of impulse associated with pain perception. produces short-acting amnesia without muscular relaxation.
Ketamine onset/duration?
less than 30 seconds / 5-10 min up to 1-2 hours
Ketamine indications?
Analgesia, treatment for severe agitation (excited delirium), procedural sedation
Ketamine contrindications?
Uncontrolled hypertension and known hypersensitivity. Avoid in patients with schizophrenia.
Ketamine side effects?
Hypertension, tachycardia, hallucinations, delusions, explicit dreams, respiratory depression
Ketamine route of administration?
IV, IO, IM, IN
Ketamine adult dose of excited delirium?
4mg/kg IM, IN
Ketamine adult dose for moderate pain?
0.5mg/kg IN; max initial dose 25mg
max cumulative dose of 100mg
Ketamine adult dose for severe pain?
0.25mg/kg IM,IV,IO; max initial dose of 25mg
max cumulative dose of 100mg
Ketamine peds dose for excited delirium?
> 2 years: 1mg/kg IV over 1 min or 3mg/kg IM
Ketamine supply?
100mg/mL in 5 mL vials
Midazolam trade name?
Versed
Versed classification?
Benzodiazepine
Versed actions?
Short acting benzodiazepine which produces CNS depression with some amnesic effects. It easily crosses the blood-brain barrier to cause deep sedation. It is 3 to 4 times as potent as Valium. It has no analgesic effects.
Versed onset/duration?
1-3 min / 2-6 hours
Versed indications?
Generalized seizures, status epilepticus, sedation prior to cardioversion or intubation
Versed contraindication?
Hypersensitivity, pregnancy, patients in shock or coma, known ETOH ingestion, and respiratory depression. Use with caution in patients with respiratory diseases such as COPD and CHF.
Versed side effects?
Respiratory depression and/or arrest is possible if given rapid IVP. Hypotension and tachycardia, especially in older adults.
Versed route of administration?
IN, IV, IO, deep IM
Versed adult dose?
IN: 0.2mg/kg; max dose of 10mg
Slow IV: 0.1mg/kg up to 10mg (usually start at 1-2.5mg)
Deep IM: 10mg (0.2mg/kg) Consider lower dose of patients with respiratory disease or patients older than 60
Versed peds dose?
0.05-0.1 mg/kg up to 5mg
Versed supply?
2, 5, 10mL vials (1mg/mL)
1, 2, 5, 10mL vials (5mg/mL)
Versed special considerations/
Flumazenil (Mazicon) is used to reverse side effects