Psych drugs Flashcards

1
Q

List the 6 typical anti-psychotics

+common suffix

A
Haloperidol
Pimozide
Trifluoperazine
Fluphenazine
Thioridazine
Chlorpromazine
(azine/azide)

(Haloed pimps & trifling thieves flew by cheating)

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2
Q

increase cAMp

block D2 receptor

A

typical anti-psychotics

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3
Q

High potency typical antipsychotics

A

Haloperidol
Trifluoperazine
Fluphenazine

(trifling Halos flew High)

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4
Q

Low potency typical antipsychotics

A

Chlorpromazine, Thioridazine

cheating theives are low

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5
Q

List 1 atypical antipsychotic and the other’s 2 common suffix

A

Aripiprazole

(+apine)(+Peridone/ idone)

asenapine, clozapine, quetipine,

iloperidone, paliperidone, risperidone, lurasidone, ziprasidone

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6
Q

serotonin (2A) and dopamine (D2) antagonist

A

Atypical antipsychotics

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7
Q

which atypical anti-psychotic is a partial D2 agonist

A

Aripiprazole

Ari is a pipsqueak and an atypical pop-star

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8
Q

causes agranulocytosis and seizures

A

Clozapine; atypical

watch clozapine closely

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9
Q

causes hyperprolactenemia (galactorrhea, amenorrhea, man boobs/ gynecomastia)

A

Risperidone; atypical

makes me think of the ice-cream a raspado. ice-cream is milky

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10
Q

causes metabolic syndrome

weight gain, dyslipidemia, diabetes

A

Clozapine
Olanzapine
Risperidone
Quetiapine

(put a CORQ in it)

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11
Q

Antipsychotics (2)

causes a prolonged QT interval

A

Ziprasidone (less EPS)

Risperidone (more EPS)

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12
Q

For treatment resistant schizophrenia &

schizophrenia associated with Suicidality

A

Clozapine

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13
Q

Clozapine can cause:
Metabolic syndrome
agranulocytosis

and what else (2)

A

Seizures

Myocarditis (angina/dyspnea)

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14
Q

Antipsychotics (2)
Causes sedation, orthostatic hypotension, &
anticholinergic side effects (dry mouth, dilated pupils, tachycardia, constipation)

A

Chlorpromazine, Thioridazine

1st gen low potency

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15
Q

Can cause sudden onset sustained muscle contractions, Dystonia. (3)

A

Haloperidol
Trifluoperazine
Fluphenazine
(typical antipsychotics high potency)

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16
Q

Can cause Tremor, Rigidity, Blunted affect, and Bradykinesia

A

Haloperidol
Trifluoperazine
Fluphenazine
(typical antipsychotics high potency)

17
Q

Can cause subjective restlessness with inability to sit still (Akathisia)

A

Haloperidol
Trifluoperazine
Fluphenazine
(typical antipsychotics high potency)

18
Q

Can cause involuntary tics or choreoathetoid movements after chronic use

A

Haloperidol
Trifluoperazine
Fluphenazine
(typical antipsychotics high potency)

19
Q

Fever, Rigidity with Hyporeflexia, mental status change, diaphoresis, Autonomic Instability
Recent use of Dopamine Antagonist

A

Neuroleptic malignant syndrome

20
Q

Schizophrenia: excess dopamine in this pathway

A

Mesolimbic

21
Q

Fever, Clonus with Hyper-reflexia, mental status change, Hypertension, tachycardia, diaphoresis
use of SSRI, MOA-I, Dextromethorphan (cough syrup)

A

Serotonin Syndrome

22
Q

Drug-induced parkinsonism is caused by dopamine (D2) receptor blockade in the ____ pathway.

A

naigrostriatal

23
Q

Drug-induced parkinsonism can be caused by (4)

A

1st gen Antipsychotics

Antiemetics/gastric motility agents
(metoclopromide, Odansetron/ prochlorepezine)

Mood stabilizers
(Valproate, Lithium)

MPTP dmg to Substantia Nigra

24
Q

Mood stabilizer for Bipolar

Manic & Depressive features

A

Lithium

25
Q

Mood stabilizer for Bipolar

Manic features only

A

Valproate, Carbamazepine

26
Q
Mood stabilizer for Bipolar
Depressive features (only)
A

Lamotrigene

27
Q
Mood stabilizer with following AE:
Nephrogenic Diabetes Insipidus
Tremor
Hypothyroidism
Teratogen (Ebstein's Anomaly)
A

Lithium

28
Q

Mood stabilizer with following AE:
Hepatotoxicity
Teratogen (neural tube defects)

A

Valproate

29
Q

Mood stabilizer with following AE:
Aplastic Anemia
SIADH
Teratogen (neural tube defects)

A

Carbamezapine

30
Q

Mood stabilizer with following AE:
Benign Rash
Steven Johnson Syndrome

A

Lamotrigene