Psych Drugs Flashcards

0
Q

tricyclics - drugs?

A
#Amitriptyline
#Nortriptyline
#Imipramine
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1
Q

SSRIs - drugs?

A
Fluoxetine
Fluvoxamine
Paroxetine
Sertraline
Citalopram
Escitalopram
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2
Q

Tricyclics - adverse affects?

A
#Dry mouth
#Arrhythmias, hypotension, confusion
#G.I. disturbances, constipation, weight gain
#Sexual side effects
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3
Q

MAOIs - drugs?

A
#Phenelzine
#isocarboxazid
#tranylcypromine
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4
Q

MAOI – Side effects?

Treatment?

A

Hypertension with food with tyramine (Red wine, aged cheese, chocolate)

Alpha blocker

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5
Q

SSRI adverse effects?

A
#Blurry vision, hypertension (opposite of tricyclics)
#G.I. disturbances, weight changes
#Sexual side effects
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6
Q

Bupropion – adverse effect?

Mirtazapine?

A

seizures

Weight gain and sedation

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7
Q

Lithium – adverse effects?

A
#Nephrotoxic, diabetes insipidus
#Thyroid dysfunction 
#Weight gain, G.I. disturbances, tremors (same as Valproic acid)
#Teratogenic (Ebstein's)
#Leukocytosis
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8
Q

Severe lithium toxicity result in?

A
#Confusion
#Ataxia
#Lethargy
#Abnormal reflexes
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9
Q

Valproic acid – adverse effects?

A
#Hepatotoxicity
#Alopecia
#Tremors, weight gain, G.I. disturbances (same as lithium)
#teratogenic (same as lithium)
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10
Q

Single Most effective treatment for depression?

A

ECT

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11
Q

Symptoms of serotonin syndrome?

A
#Cognitive – agitation, confusion, hallucinations, hypomania
#Autonomic – sweating, hyperthermia, tachycardia, nausea/diarrhea, shivering
#Somatic – tremors, myoclonus
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12
Q

Treatment of serotonin syndrome?

A
#stop SSRI and symptomatic treatment
#Cyproheptadine (serotonin antagonist)
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13
Q

MAOI in pregnancy - do you stop it?

A

Yes

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14
Q

Long QT in MAOI - treatment?

A

sodium bicarbonate

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15
Q

SSRI discontinuation syndrome?

A
#dizziness
#paresthesias
16
Q

Psychiatric drug class that inhibits platelet aggregation?

Which specific drug is contraindicated in pregnancy?

A

SSRIs;

Paroxetine

17
Q

Weight gain bigger problem with which SSRI?

A

Paroxetine

18
Q

SSRIs that is most likely to have drug-drug interactions? Least likely?

A

Fluoxitene and paroxetine

Citalopram and escitalopram

19
Q

Bupropion - MoA?

A

Increase dopamine and NE

20
Q

Bupropion - indications? Contraindications?

Do not give to? Why?

A

SAD, depression, smoking cessation

Seizures

Anorexics, alcoholics, epileptics; seizures

21
Q

Side effects of bupropion?

A

Headache, weight loss, insomnia, ANXIETY, SEIZURES

22
Q

Venlafaxine- MoA?

Complications?

A

SNRI (SSRI at lower doses)

SSRI side effects - decreased libido, erectile dysfunction, headaches, insomnia, “weird, wired, funny” feeling,

NE side effects - hypertension, xerostomia

23
Q

Duloxetine - mechanism? Indications?

Do not take if?

A

Bicyclic SNRI;

Neuropathic pain, MDD, fibromyalgia, musculoskeletal pain, urinary incontinence

Liver disease

24
Q

Duloxetine vs Venlafaxine?

A

SNRI vs SNRI at higher doses

Same side effects but Duloxetine also has worse nausea, and liver damage

25
Q

Anxious, cachectic, depressed old lady - consider?

A

Mirtazapine - increased weight gain/appetite, will make drowsy

26
Q

Valproic acid - side effects?

A

GI disturbances&raquo_space;> neurologic, opthamalogic