Psych Flashcards
Which 2 meds are approved for autism spectrum disorder?
risperidone and aripiprazole for aggression
What is the best treatment for ADHD?
Atomoxetine (norepinephrine reuptake inhibitor) because better side effect profile than methylphenidate/dextroamphetamine (stimulants)
Disruptive Mood Dysregulation Disorder
Chronic, severe, persistent irritability w/ temper outbursts
Must be almost every day w/o period > 3 mo without symptoms
Out of proportion to situation
What sleep disturbances are associated w/ MDD?
Dec REM latency
Inc REM sleep
What is first line for MDD? What are some Alt Med Regimens for MDD?
1 = SSRI
If also have neuropathic pain - duloxetine (NE reuptake inhibitor)
If afraid of wt gain and sex side effects - bupropion
If smoking cessation - buproprion
If also trouble with sleeping - mirtazapine (sedation)
If atypical features (inc sleep, inc wt, inc appetite, worse in evening, feel heavy) - MAOIs (phenelzine, isocarboxazid, tranylcypromine)
Side Effect of Buproprion
lowers seizure threshold
Bipolar 1 v. 2
1 - mania (1 wk, warrant hospitalization) + depression
2- hypomania (< 1 wk, no hospitalization) + depression
Tx of bipolar disorder in pregnancy
may use lurasidone
Persistent Depressive Disorder
Depressed mood almost every day for > 2 yrs but less severe
Tx = SSRI + CBT
Cyclothymic Disorder
Hypomania + mild depression for > 2 yrs
Tx = lithium, valproic acid, antipsychotics + CBT
How do you tell normal bereavement v. MDD?
Normal = sad, worried about dead, dec sleep, tearful; 6 mo - 1 yr, tx is therapy alone
Red Flags = thoughts of death, morbid, marked psychomotor slowing, psychosis, functional impairment for long period of time, sx > 2 wks
Lithium Toxicity
Confusion, ataxia, lethargy, abnormal reflexes
What is the most effective treatment of depression?
ECT
Serotonin Syndrome + Tx
- agitation, confusion, hallucinations, hypomania
- autonomics (sweating, tachy, hyperthermia, nausea, diarrhea, shivering)
- Tremor, myoclonus
Tx = stop meds, CYPROHEPTADINE
What is the first line therapy for schizophrenia?
Atypical antipsychotics
- olanzapine, ziprasidone (short-acting, IM in emergency)
- risperidone and paliperidone (long-acting, good if low compliance)
- others … quetiapine, apiprazole, asenapine, iloperidone
- lurasidone in pregnancy