psych Flashcards

1
Q

Alzheimer: NT changes

A

Decreased ACh, increased glutamate

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2
Q

Anxiety: NT changes

A

Increased NE, decreased GABA, 5-HT

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3
Q

Depression: NT changes

A

Decreased NE, decreased 5-HT, dopamine

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4
Q

Huntington disease: NT changes

A

Decreased GABA, ACh, increased DA

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5
Q

Parkinson dz: NT changes

A

Decreased DA, increased ACh

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6
Q

Schizophrenia: NT canges

A

Increased DA

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7
Q

Dementia:anzapine reversible causes

A

Hypothyroidism, depression, B12 deficiency, NPH

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8
Q

Depression: Sleep changes

A

Decreased slow-wave sleep, REM latency, increased REM early in sleep cycle, increased total REM sleep, repeated nighttime awakenings, early-morning wakening

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9
Q

Difference between malingering and factitious disorder

A

Former ceases after gains are made

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10
Q

three types of personality disorders

A

Weird, wild, worrying

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11
Q

SE: olanzapine, clozapine, risperidone

A

Weight gain; weight gain, agranulcytosis, seizure; prolactinemia (irregular menstration and fertlity issues); all prolong QT interval

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12
Q

Typical psychotic clinical indications

A

schizophrenia, psychosis, mania, Tourette

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13
Q

Atypical antipsychotics clinical indications

A

Same as typical; but also negative symptoms of schizophrenia, bipolra disorder, depression, OCD, anxiety disorder

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14
Q

NMS FEVER

A

Fever, encephalopathy, vitals unstable, enzymes (increased myglobinuria), rigidity of muscles

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15
Q

Diuretic associated with Li toxicity

A

Thiazide diuretics

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16
Q

Buspirone MOA

A

Stimulates 5-HT-1a receptors, rx for GAD with no sedation, addiction, or tolerance; need 1-2 weeks to take effect; no interaction with alcohol

17
Q

Buproprione unique characteristics

A

Atypical antidepressant: no sexual side effects, seizures in anorexic/bulemic patients

18
Q

Mirtazapine unique characteristics

A

Atypical antidepressant: Sedation, increased appetite (better for weight gain), dry mouth

19
Q

Trazodone

A

Atypical antidepressant: sedation (good for insomnia), priaprism