PSY313 unit test 1 (2) Flashcards

1
Q

Why do cells age?

A

well because a cell cannot live once the telomere is gone.

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2
Q

What are telomeres and how do they play a role in aging?

A

A telomere is kind of like the plastic around a shoelace, it protects our genetic data allowing cells to divide without losing important information, everytime a cell divides the telomere gets a little shorter eventually becoming so short that they can no longer divide and die.

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3
Q

Can telomeres be longer on some people

A

Yes, but we are not sure why.

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4
Q

what accelerates telomere shortening?

A

cellular stress increases the rate of telomere shortening (e.g., toxins from environment, lack of nutrients, excess of free radicals..)

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5
Q

What are free radicals and how do they affect cells?

A

Free radicals are unstable molecules that attach to cells and damage them, accelerating aging and cell death.

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6
Q

What is a natural source of free radicals in the body?

A

Free radicals are a natural consequence of our metabolism.

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7
Q

How does the body defend against free radicals?

A

The body is designed to neutralize free radicals using antioxidants, which help prevent diseases

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8
Q

What environmental factors increase free radicals in the body?

A

Environmental stressors such as poor diet, pollutants, and chronic stress increase free radical production.

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9
Q

Do antioxidants slow aging?

A

While antioxidants have many health benefits, there is no convincing evidence that they play a role in significantly slowing the aging process.

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10
Q

Is aging inevitable according to current scientific understanding?

A

Aging is considered a natural part of cellular life, and cells are designed to only live for a specific duration.

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11
Q

Is there a debate about maximum human longevity?

A

Some experts believe that maximum longevity is increasing, while others think that humans have already reached their maximum possible age.

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12
Q

What are common misconceptions about brain aging?

A

Many believe that as we age, there’s widespread neural fallout and loss of neurons, but this isn’t true. Neuron loss is limited to localized areas only.

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13
Q

Does neurogenesis occur in adults?

A

Yes, contrary to the myth that we stop generating new neurons after birth, the hippocampus continues to show neurogenesis throughout life.

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14
Q

What is the role of the hippocampus in memory?

A

The hippocampus is crucial for forming memories but not for storing them. It is one of the areas where cell loss can occur with age.

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15
Q

Which brain areas are commonly affected by aging?

A

Aging typically affects the hippocampus, prefrontal cortex, and cerebellum, leading to deficits in memory, planning, balance, and fine motor control.

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16
Q

What functions are the prefrontal cortex and cerebellum associated with?

A

The prefrontal cortex is related to memory and complex planning, while the cerebellum is important for balance and fine motor control.

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17
Q

How do diet and exercise impact brain health?

A

A healthy diet and regular exercise are vital for maintaining brain function and preventing neural loss, helping to offset the effects of aging on the brain.

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18
Q

How does aerobic exercise affect brain volume in seniors compared to stretching and strength training?

A

Seniors who engage in aerobic exercise show greater brain volume in specific areas compared to those who do stretching and strength training, indicating the positive impact of aerobic activities on brain health.

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19
Q

What is the relationship between hippocampal volume and fitness?

A

There is a positive relationship between the size of the hippocampus and fitness levels; better fitness is associated with a larger hippocampus.

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20
Q

How does fitness affect memory scores?

A

Fitness explains some part of the memory score, with the effect of fitness on memory being mediated by the volume of the left hippocampus. This means that a larger hippocampus, encouraged by higher fitness levels, supports better memory.

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21
Q

How does the hippocampus mediate the relationship between fitness and memory?

A

Fitness supports brain health, which in turn supports memory. The larger your hippocampus (as a result of being fitter), the better your memory performance tends to be.

22
Q

What changes occur in white matter with age, and what do they indicate?

A

With age, white matter can show hyperintensities, which are bright spots on MRIs indicating damage. These damages are related to disease and are not a natural consequence of aging.

23
Q

How do brain activity patterns differ between older and younger adults?

A

Older adults use more of their brain (bilateral activation) to accomplish the same tasks as younger adults (unilateral activation), allowing them to match younger performance despite age-related changes like cell loss in the prefrontal cortex.

24
Q

Do older adults generally see a reduction in psychological and social well-being?

A

No, the majority of older adults do not see a reduction in psychological and social well-being. In fact, older adults are often more satisfied with their lives than younger individuals.

25
Q

What are the main changes in skin as we age?

A

As we age, skin loses fat from the fat layer, causing sagging and loss of plumpness. The skin also becomes drier and loses elasticity. These changes are largely inevitable.

26
Q

What are the three main layers of the skin and their functions?

A

The three main layers are:
Epidermis: The outer protective layer.
Dermis: The thickest layer containing touch receptors, hair follicles, and nerve endings.
Fat Layer: Gives the skin its plump look.

27
Q

What factors influence the age at which we develop wrinkles and lose skin structure?

A

The development of wrinkles and loss of skin structure are largely dependent on genetics and environmental factors, with smoking and sun exposure being the two biggest culprits.

28
Q

What changes occur in hair as we age?

A

Changes in hair color and volume (greying and thinning) are inevitable as we age, with these changes being almost exclusively determined by genes.

29
Q

How can changes in skin and hair impact psychological well-being?

A

Changes in skin and hair, such as wrinkling, loss of volume, and greying, can lead to psychological effects, affecting how individuals feel about their aging appearance.

30
Q

What is presbyopia?

A

Presbyopia is a common condition related to aging where the eye’s lens loses its ability to focus properly, making it difficult to see close objects. It often starts in a person’s 40s.

31
Q

What happens to the lens of the eye as we age?

A

As we age, the lens of the eye becomes less flexible and less able to change shape to focus on close objects. For distant objects, the lens is thin and flat, and for close objects, it needs to be round and fat. Presbyopia results from the lens losing this ability.

32
Q

Why does vision become more difficult in the dark as we age?

A

Vision in the dark worsens with age because the pupil, which controls light entry, doesn’t change size as quickly due to weakened iris muscles, reducing low-light vision and increasing susceptibility to glare.

33
Q

What are cataracts and how common are they in older adults?

A

Cataracts are protein deposits on the lens of the eye that cause blurry vision. They affect about 22% of Canadians up to age 80 and 30% over age 80. Cataracts are generally easy to remove through surgery.

34
Q

What is macular degeneration and its impact?

A

Macular degeneration is a major cause of blindness in individuals over 80, involving the deterioration of receptors in the macula (the central part of the retina), leading to central vision loss while peripheral vision is maintained. There is currently no treatment, and the causes are not well understood.

35
Q

How does presbyopia affect daily activities?

A

Presbyopia can lead to difficulties with driving (vehicle accidents), increased risk of falls, and challenges in social interactions due to impaired near vision.

36
Q

What is presbycusis?

A

Presbycusis is age-related hearing loss that involves the loss of auditory neurons, primarily affecting the ability to hear high frequencies. It is not inevitable for everyone.

37
Q

Why are high frequencies lost more than low frequencies in presbycusis?

A

High frequency sounds stimulate high frequency receptors more than low frequency sounds. These receptors are used more and are thus more prone to damage, especially in noisy environments.

38
Q

Does taste decline with age?

A

Taste itself does not decline significantly with age, though there are changes in flavor perception due to factors like reduced smell.

39
Q

What happens to the sense of smell as we age?

A

There is a reduction in smell due to the loss of olfactory receptors. By the age of 80, about three-quarters of people experience a significant loss of smell.

40
Q

What are some major physical changes that occur with aging?

A

Aging can lead to height loss due to bone loss in the vertebrae, changes in body mass index (BMI), and a decrease in free fat mass (FFM). Muscle fibers decrease in number and size, starting in the 60s.

41
Q

What happens to bones as we age?

A

Bones lose density and become porous, starting in the 30s. Women lose more bone mass than men due to factors like smaller bone size and dietary habits.

42
Q

How does the heart change with age?

A

The heart muscles and arteries become stiffer, reducing the heart’s flexibility and aerobic capacity, which declines about 10% per decade. This can be slowed by aerobic exercise.

43
Q

What is the relationship between aging and cardiovascular disease?

A

Cardiovascular disease, which includes conditions like heart attacks and strokes, is a leading cause of death. It results from the buildup of fat in the arteries and changes in heart function.

44
Q

What is climacteric in the context of aging?

A

Climacteric refers to the phase in life where individuals, both women and men, are no longer able to reproduce. Women experience this during menopause and men during andropause, though men’s changes are less extreme.

45
Q

What are common symptoms associated with menopause?

A

Hot flashes, night sweating, headaches, insomnia, irritability, mood swings, depression, and memory loss.

46
Q

What changes occur in the vaginal tissues during menopause?

A

Tissues in the vagina become thinner, drier, and less able to produce secretions.

47
Q

What are some health risks that increase after menopause?

A

Weak bones, high blood pressure, cardiovascular disease.

48
Q

What risks are associated with hormone replacement therapy?

A

Increased rates of breast cancer and stroke, as research since 2002 has shown.

49
Q

What is andropause, and what are its effects?

A

Andropause is the process of the reduction of testosterone in men, which can lead to decreased bone density, muscle strength, and mass.

50
Q

What are the benefits and risks of testosterone replacement in older men?

A

Testosterone replacement is associated with increased bone density and muscle strength, but it was once considered unnecessary and dangerous. (prostate issues, and cadrio prob)

51
Q

What causes erectile dysfunction in older men?

A

Erectile dysfunction occurs in about 40% of men over 65, but it is more commonly associated with diseases rather than aging per se.